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首页> 外文期刊>Journal of bacteriology >Nucleotide sequences of the genes encoding type 1 fimbrial subunits of Klebsiella pneumoniae and Salmonella typhimurium.
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Nucleotide sequences of the genes encoding type 1 fimbrial subunits of Klebsiella pneumoniae and Salmonella typhimurium.

机译：编码肺炎克雷伯菌和鼠伤寒沙门氏菌1型纤维亚基的基因的核苷酸序列。

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摘要

The nucleotide sequences of the genes encoding the subunits of Klebsiella pneumoniae and Salmonella typhimurium type 1 fimbriae were determined. Comparison of the predicted amino acid sequences of the two subunits revealed domains in which the sequences were highly conserved. Both gene products possessed signal peptides, a fact consistent with the transport of the fimbrial subunit across the membrane, but these regions showed no amino acid homology between the two proteins. The predicted N-terminal amino acid sequences of the processed fimbrial subunits were in good agreement with those obtained by purification of the fimbrial subunits.
机译：确定了编码肺炎克雷伯菌和鼠伤寒沙门氏菌1型菌毛的亚基的基因的核苷酸序列。两个亚基的预测氨基酸序列的比较揭示了其中序列高度保守的结构域。两种基因产物都具有信号肽，这一事实与纤维亚基跨膜的运输是一致的，但是这些区域在两种蛋白之间没有显示出氨基酸同源性。经加工的纤维亚基的预测的N-末端氨基酸序列与通过纯化纤维亚基获得的序列非常一致。

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