Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium.

N Zhu; B M Olivera; J R Roth

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Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium.

机译：pnuC基因的遗传特征，该基因编码鼠伤寒沙门氏菌中烟酰胺单核苷酸转运系统的组成部分。

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The pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system, has been mapped and oriented. The gene order of the pnuC region, which is at min 17 of the Salmonella chromosome, is nadA-pnuC-aroG-gal. Polarity tests, with pnuC::Mu d-lac operon fusions, reveal that the pnuC gene is the promoter distal gene in an operon with the nadA gene, which encodes the second enzyme of the pyridine biosynthetic pathway. The nadA pnuC operon is regulated by the NadI repressor. The pnuC gene also has its own promoter, since strains with a nadA::Tn10d(Tc) insertion still express the pnuC gene at a low, unregulated level.

机译：编码烟酰胺单核苷酸转运系统组分的pnuC基因已作图和定位。位于沙门氏菌染色体第17分钟的pnuC区的基因顺序是nadA-pnuC-aroG-gal。用pnuC :: Mu d-lac操纵子融合体进行的极性测试显示，在与nadA基因的操纵子中，pnuC基因是操纵子的远端基因，该基因编码吡啶生物合成途径的第二种酶。 nadA pnuC操纵子受NadI阻遏物调控。 pnuC基因也有其自己的启动子，因为插入nadA :: Tn10d（Tc）的菌株仍然以低水平，不受调控的水平表达pnuC基因。

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《Journal of bacteriology》 |1989年第8期|共8页
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N Zhu; B M Olivera; J R Roth;
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5. Genetic identification and characterization of genes involved in the 2-C-methyl-D-erythritol 4-phosphate pathway for early isoprenoid biosynthesis in Salmonella typhimurium. [D] . Cornish, Rita Marie. 2003

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6. Genetic characterization of the pnuC gene which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium. [O] . N Zhu, B M Olivera, J R Roth 1989

机译：pnuC基因的遗传特征该基因编码鼠伤寒沙门氏菌中烟酰胺单核苷酸转运系统的组成部分。
7. Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium. [O] . Zhu, N, Olivera, B M, Roth, J R 1989

机译：pnuC基因的遗传特征，该基因编码鼠伤寒沙门氏菌中烟酰胺单核苷酸转运系统的组成部分。
8. Genetic and Biochemical Characterization of Distinct Transport Systems for Uracil, Uridine and Cytidine in Salmonella Typhimurium [R] . Williams, J. C., Lee, C. E., Wild, J. R. 1979

机译：鼠伤寒沙门氏菌尿嘧啶，尿苷和胞苷不同转运系统的遗传和生化特征

Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium.

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