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首页> 外文期刊>Journal of bacteriology >Role of the two-component signal transduction and the phosphoenolpyruvate: carbohydrate phosphotransferase systems in competence development of Haemophilus influenzae Rd.
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Role of the two-component signal transduction and the phosphoenolpyruvate: carbohydrate phosphotransferase systems in competence development of Haemophilus influenzae Rd.

机译:两组分信号转导和磷酸烯醇式丙酮酸:碳水化合物磷酸转移酶系统在流感嗜血杆菌Rd能力发展中的作用。

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摘要

Haemophilus influenzae Rd becomes competent for transformation by nutritional downshift or transient anaerobic growth through a process that requires cyclic AMP receptor protein and adenylate cyclase. Insertion mutations in crr or ptsI of the phosphoenolpyruvate:carbohydrate phosphotransferase system lowered transformation frequencies, and the effect was reversed by the addition of cyclic AMP. However, insertions into H. influenzae homologs of two-component signal transduction genes had no effect on competence.
机译:流感嗜血杆菌Rd可通过需要环AMP受体蛋白和腺苷酸环化酶的过程,通过营养下降或瞬时厌氧生长来转化。磷酸烯醇丙酮酸:碳水化合物磷酸转移酶系统的crr或ptsI中的插入突变降低了转化频率,并且通过添加环状AMP逆转了该作用。然而,将两组分信号转导基因插入流感嗜血杆菌同源物中对能力没有影响。

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