The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus.

N Tojo; S Inouye; T Komano

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The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus.

机译：lonD基因与编码ATP依赖型蛋白酶的lon基因同源，对于发展粘液黄球菌至关重要。

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Myxococcus xanthus contains two genes (lonV and lonD) homologous to the Escherichia coli lon gene for an ATP-dependent protease. We found that the lonD gene encodes a 90-kDa protein consisting of 827 amino acid residues. The lonD gene product shows 49, 48, and 52% sequence identity to the products of the M. xanthus lonV, E. coli lon, and Bacillus brevis lon genes, respectively. When a lonD-lacZ fusion was used, lonD was expressed during both vegetative growth and development. However, while lonD-disrupted strains were able to grow normally vegetatively, the development of M. xanthus was found to be arrested at an early stage in these strains. The mutant strains were able to form neither fruiting bodies nor myxospores.

机译：Xanthus粘球菌含有两个与ATP依赖性蛋白酶的大肠埃希氏菌lon基因同源的基因（lonV和lonD）。我们发现lonD基因编码由827个氨基酸残基组成的90 kDa蛋白。 lonD基因产物分别显示出与黄腐分支杆菌lonV，大肠杆菌lon和短芽孢杆菌lon基因的产物49、48和52％的序列同一性。当使用lonD-lacZ融合体时，在营养生长和发育期间都表达了lonD。但是，尽管被lonD破坏的菌株能够正常地营养生长，但是发现在这些菌株的早期阶段，M。xanthus的发育被阻止了。突变菌株既不能形成子实体也不能形成粘孢子。

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《Journal of bacteriology》 |1993年第14期|共5页
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N Tojo; S Inouye; T Komano;
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1. Myxococcus xanthus encodes an ATP-dependent protease which is required for developmental gene transcription and intercellular signaling. [J] . R E Gill, M Karlok, D Benton Journal of bacteriology . 1993,第14期

机译：黄腐粘球菌编码一种ATP依赖性蛋白酶，这是发育基因转录和细胞间信号转导所必需的。
2. Two homologous genes coding for spore-specific proteins are expressed at different times during development of Myxococcus xanthus. [J] . M Teintze, R Thomas, T Furuichi, Journal of bacteriology . 1985,第1期

机译：在黄色粘球菌的发育过程中的不同时间表达两个编码孢子特异性蛋白的同源基因。
3. Identification and characterization of spdR mutations that bypass the BsgA protease-dependent regulation of developmental gene expression in Myxococcus xanthus. [J] . Hager E, Tse H, Gill RE Molecular Microbiology . 2001,第3期

机译：spdR突变的鉴定和表征，该突变绕过了黄色粘球菌中BsgA蛋白酶依赖性的发育基因表达调控。
4. Disruption of tobacco chloroplast clpP gene encoding a proteolytic subunit of ATP-dependent protease [C] . T Shikanai, K Shimizu, K Ueda International Congress on Photosynthesis . 2001

机译：烟草叶绿体CLPP基因的破坏编码ATP依赖性蛋白酶的蛋白水解亚基
5. Studies on the regulation of the tps andops genes during development of Myxococcus xanthus. [D] . Kil, Ki-Soo. 1991

机译：关于黄花粘球菌发育过程中tps andops基因调控的研究。
6. The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus. [O] . N Tojo, S Inouye, T Komano 1993

机译：lonD基因与编码ATP依赖型蛋白酶的lon基因同源对于发展粘液黄球菌至关重要。
7. The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus. [O] . Tojo, N, Inouye, S, Komano, T 1993

机译：lonD基因与编码ATP依赖型蛋白酶的lon基因同源，对于发展粘液黄球菌至关重要。

The lonD gene is homologous to the lon gene encoding an ATP-dependent protease and is essential for the development of Myxococcus xanthus.

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