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首页> 外文期刊>Journal of bacteriology >Effect of decoyinine on the regulation of alpha-amylase synthesis in Bacillus subtilis.
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Effect of decoyinine on the regulation of alpha-amylase synthesis in Bacillus subtilis.

机译：辅酶对枯草芽孢杆菌中α-淀粉酶合成的调节作用。

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摘要

Decoyinine, an inhibitor of GMP synthetase, allows sporulation in Bacillus subtilis to initiate and proceed under otherwise catabolite-repressing conditions. The effect of decoyinine on alpha-amylase synthesis in B. subtilis, an event which exhibits regulatory features resembling sporulation initiation, was examined. Decoyinine did not overcome catabolite repression of alpha-amylase synthesis in a wild-type strain of B. subtilis but did cause premature and enhanced synthesis in a mutant strain specifically blocked in catabolite repression of alpha-amylase synthesis. Decoyinine had no effect on alpha-amylase enzymatic activity. Thus, it appears that the catabolite control mechanisms governing alpha-amylase synthesis and sporulation in B. subtilis differ in their responses to decoyinine and hence must consist at least partially of separate components.
机译：Decoyinine是GMP合成酶的抑制剂，它可使枯草芽孢杆菌中的孢子形成，并在抑制分解代谢物的条件下继续进行。考察了地考宁对枯草芽孢杆菌α-淀粉酶合成的影响，该事件表现出类似于孢子形成起始的调控特征。 Decoyinine不能克服枯草芽孢杆菌野生型菌株中分解代谢物对α-淀粉酶合成的抑制作用，但确实会导致突变体菌株的过早合成和增强合成，而该突变体菌株在分解代谢物抑制α-淀粉酶合成中被特异性阻断。 Decoyinine对α-淀粉酶的酶活性没有影响。因此，似乎在枯草芽孢杆菌中控制α-淀粉酶合成和孢子形成的分解代谢控制机制在其对辅嘌呤的反应方面有所不同，因此必须至少部分地由单独的组分组成。

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