Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.

J Martinussen; P Glaser; P S Andersen; H H Saxild

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Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.

机译：枯草芽孢杆菌中存在两个编码尿嘧啶磷酸核糖基转移酶的基因。

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Uracil phosphoribosyltransferase (UPRTase) catalyzes the key reaction in the salvage of uracil in many microorganisms. Surprisingly, two genes encoding UPRTase activity were cloned from Bacillus subtilis by complementation of an Escherichia coli mutant. The genes were sequenced, and the putative amino acid sequences were deduced. One gene showed a high level of homology to UPRTases from other organisms, whereas the other gene with a low level of homology to other UPRTases turned out to be the pyrR gene--the repressor of the pyr operon. The role of these genes in uracil metabolism was established by an analysis of the phenotypes of upp and pyrR mutants.

机译：尿嘧啶磷酸核糖基转移酶（UPRTase）催化许多微生物对尿嘧啶的抢救中的关键反应。令人惊讶地，通过互补大肠杆菌突变体从枯草芽孢杆菌克隆了编码UPRTase活性的两个基因。对基因进行测序，并推定推测的氨基酸序列。一个基因与其他生物的UPRTase具有高水平的同源性，而另一个基因与其他UPRTase的同源性低的事实证明是pyrR基因-pyr操纵子的阻遏物。这些基因在尿嘧啶代谢中的作用是通过分析upp和pyrR突变体的表型来确定的。

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《Journal of bacteriology》 |1995年第1期|共4页
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J Martinussen; P Glaser; P S Andersen; H H Saxild;
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1. Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis. [J] . J Martinussen, P Glaser, P S Andersen, Journal of bacteriology . 1995,第1期

机译：枯草芽孢杆菌中存在两个编码尿嘧啶磷酸核糖基转移酶的基因。
2. Tricistronic operon expression of the genes gcaD (tms), which encodes N-acetylglucosamine 1-phosphate uridyltransferase, prs, which encodes phosphoribosyl diphosphate synthetase, and ctc in vegetative cells of Bacillus subtilis. [J] . I Hilden, B N Krath, B Hove-Jensen Journal of bacteriology . 1995,第24期

机译：三顺反子操纵子在枯草芽孢杆菌营养细胞中表达的基因gcaD（tms），其编码N-乙酰氨基葡糖1-磷酸尿嘧啶转移酶，prs，其编码磷酸核糖二磷酸合成酶和ctc。
3. Functional characterization of a gene encoding a dual domain for uridine kinase and uracil phosphoribosyltransferase in Arabidopsis thaliana [J] . M. Rafiqul Islam, Hoyeun Kim, Shin-Wook Kang, Plant Molecular Biology . 2007,第4期

机译：拟南芥中编码尿苷激酶和尿嘧啶磷酸核糖基转移酶双结构域的基因的功能表征
4. Bioinformatics Analysis and Characteristics of Uracil-DNA glycosylase encoded by UL2 Gene from duck plague virus [C] . Xueqin Yin, Anchun Cheng, Mingshu Wang, ICCEE 2010;International conference on computer and electrical engineering . 2010

机译：鸭瘟病毒UL2基因编码的尿嘧啶DNA糖基化酶的生物信息学分析及特征
5. Cloning and characterization of the yjeA gene encoding a novel secretory DNase, YjeA, from Bacillus subtilis. [D] . Ng, Ka Lun. 2007

机译：枯草芽孢杆菌中编码新型分泌型DNase YjeA的yjeA基因的克隆和鉴定。
6. Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis. [O] . J Martinussen, P Glaser, P S Andersen, 1995

机译：枯草芽孢杆菌中存在两个编码尿嘧啶磷酸核糖基转移酶的基因。
7. Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis. [O] . Martinussen, J, Glaser, P, Andersen, P S, 1995

机译：枯草芽孢杆菌中存在两个编码尿嘧啶磷酸核糖基转移酶的基因。
8. Synthesis of DNA Containing Uracil During Bacteriophage Infection of Bacillus Subtilis. Final Report (12TH Year) [R] . Price, A. R. 1983

机译：枯草芽孢杆菌噬菌体感染过程中含尿嘧啶DNa的合成。最终报告（第12年）

Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.

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