A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2

Jennifer C. Miller; James L. Bono; Kelly Babb; Nazira El-Hage; Sherwood Casjens; Brian Stevenson

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A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2

机译：伯氏疏螺旋体B31株中eppA的第二个等位基因位于先前未检测到的环状质粒cp9-2上

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Although sequence analysis of Borrelia burgdorferiisolate B31 was recently declared “complete,” we found that cultures of this strain can contain a novel 9-kb circular plasmid, cp9-2. The newly described plasmid contains both sequence similarities with and differences from the previously identified B31 plasmid cp9-1 (formerly cp9). cp9-1 and cp9-2 each encode a unique allele of EppA, a putative membrane protein synthesized by B. burgdorferiduring mammalian infection.

机译：尽管最近宣布了勃氏疏螺旋体分离株B31的序列分析是“完整的”，但我们发现该菌株的培养物可以包含新型的9-kb环状质粒cp9-2。新描述的质粒包含与先前鉴定的B31质粒cp9-1（以前称为cp9）的序列相似性和差异。 cp9-1和cp9-2各自编码EppA的独特等位基因，EppA是由 B合成的推定膜蛋白。哺乳动物感染期间的伯格氏病。 展开▼

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《Journal of bacteriology》 |2000年第21期|共5页

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Jennifer C. Miller; James L. Bono; Kelly Babb; Nazira El-Hage; Sherwood Casjens; Brian Stevenson;
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中图分类微生物学;

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1. The cryptic ospC gene of Borrelia burgdorferi B31 is located on a circular plasmid. [J] . A Sadziene, B Wilske, M S Ferdows, Infection and immunity . 1993,第5期

机译：伯氏疏螺旋体B31的隐性ospC基因位于环状质粒上。

2. Decreased Infectivity in Borrelia burgdorferi Strain B31 Is Associated with Loss of Linear Plasmid 25 or 28-1 [J] . Maria Labandeira-Rey, Jonathan T. Skare Infection and immunity . 2001,第1期

机译：伯氏疏螺旋体B31株的感染力降低与线性质粒25或28-1的丢失有关

3. A family of genes located on four separate 32-kilobase circular plasmids in Borrelia burgdorferi B31. [J] . B Stevenson, K Tilly, P A Rosa Journal of bacteriology . 1996,第12期

机译：位于伯氏疏螺旋体B31中四个单独的32碱基对环状质粒上的基因家族。

4. Plasmid-encoded virulence determinants of Borrelia burgdorferi. [D] . Purser, Joye Elizabeth. 2002

机译：伯氏疏螺旋体的质粒编码毒力决定簇。

5. Note: A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2 [O] . Jennifer C. Miller, James L. Bono, Kelly Babb, 2000

机译：注意：伯氏疏螺旋体B31株中eppA的第二个等位基因位于先前未检测到的环状质粒cp9-2上

6. A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2 [O] . Miller, Jennifer C., Bono, James L., Babb, Kelly, 2000

机译：伯氏疏螺旋体B31株中eppA的第二个等位基因位于先前未检测到的环状质粒cp9-2上

1. Isolation and recultivation of pathogenic Borrelia burgdorferi strain, pathogenic Borrelia burgdorferi [P] . 外国专利： JP3328644B2 . 2002-09-30

机译：致病性伯氏疏螺旋体菌株的分离和再培养

2. PATHOGENIC BORRELIA BURGDORFERI STRAIN, METHOD FOR ISOLATING AND RECULTURING PATHOGENIC BORRELIA BURGDORFERI [P] . 外国专利： JP2001069969A . 2001-03-21

机译：致病性鲍氏疏螺旋体菌株，分离和恢复致病性鲍氏疏螺旋体的方法

3. IMMUNOLOGICALLY ACTIVE PROTEINS FROM BORRELIA BURGDORFERI, RELATED TEST KITS WHICH CONTAIN THESE PROTEINS AND ARE SUITABLE FOR DETECTING ANTIBODIES IN TEST FLUIDS, AND THE USE OF THESE PROTEINS AS VACCINES AGAINST INFECTIONS CAUSED BY BORRELIA STRAINS [P] . 外国专利： CA2072008C . 2003-01-28

机译：伯氏疏螺旋体，包含这些蛋白且适合检测测试液中抗原的相关测试试剂盒的免疫活性蛋白，以及将这些蛋白用作疫苗以预防葡萄球菌引起的感染

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A Second Allele of eppA in Borrelia burgdorferi Strain B31 Is Located on the Previously Undetected Circular Plasmid cp9-2

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