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首页> 外文期刊>Journal of bacteriology >Virulence and the Environment: a Novel Role for Vibrio cholerae Toxin-Coregulated Pili in Biofilm Formation on Chitin
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Virulence and the Environment: a Novel Role for Vibrio cholerae Toxin-Coregulated Pili in Biofilm Formation on Chitin

机译:毒力与环境:霍乱弧菌毒素促成核菌毛在甲壳质生物膜形成中的新作用。

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摘要

The toxin-coregulated pilus (TCP) of Vibrio cholerae is required for intestinal colonization and cholera toxin acquisition. Here we report that TCP mediates bacterial interactions required for biofilm differentiation on chitinaceous surfaces. We also show that undifferentiated TCP? biofilms have reduced ecological fitness and, thus, that chitin colonization may represent an ecological setting outside the host in which selection for a host colonization factor may take place.
机译:霍乱弧菌霍乱弧菌的毒素堆积菌毛(TCP)是肠道定殖和霍乱毒素获取所必需的。在这里我们报告说,TCP介导了几丁质表面生物膜分化所需的细菌相互作用。我们还显示未分化的TCP ?生物膜具有降低的生态适应性,因此,几丁质定植可能代表宿主外部的生态环境,在该环境中可能发生宿主定殖因子的选择。

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