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APS -70th Annual Meeting of the APS Division of Fluid Dynamics- Event - Lagrangian coherent structures in the left ventricle in the presence of aortic valve regurgitation

机译:APS-流体动力学APS部门第70届年会-事件-主动脉瓣关闭不全时左心室的拉格朗日相干结构

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Aortic valve regurgitation is a rather prevalent condition where the aortic valve improperly closes, allowing filling of the left ventricle of the heart to occur partly from backflow through the aortic valve. Although studies of intraventricular flow are rapidly gaining popularity in the fluid dynamics research community, much attention has been given to the left ventricular vortex and its potential for early detection of disease, particularly in the case of dilated cardiomyopathy. Notably, the subsequent flow in the left ventricle in the presence of aortic valve regurgitation ought to be appreciably disturbed and has yet to be described. Aortic valve regurgitation was simulated extit{in vitro} in a double-activation left heart duplicator and the ensuing flow was captured using two-dimensional time-resolved particle image velocimetry. Further insight into the regurgitant flow is obtained by computing attracting and repelling Lagrangian coherent structures. An interesting interplay between the two inflowing jets and their shear layer roll-up is observed for various grades of regurgitation. This study highlights flow features which may find use in further assessing regurgitation severity.
机译:主动脉瓣关闭不全是一种相当普遍的情况,主动脉瓣关闭不当,导致心脏左心室的充盈部分由通过主动脉瓣的回流引起。尽管脑室内流量的研究在流体动力学研究界迅速得到普及,但人们对左心室旋涡及其早期发现疾病的潜力给予了极大关注,特别是在扩张型心肌病的情况下。值得注意的是,在存在主动脉瓣关闭不全的情况下,随后在左心室的血流应该受到明显干扰,并且有待描述。主动脉瓣关闭不全在体外模拟在双重激活左心脏复制器中,并使用二维时间分辨粒子图像测速仪捕获随后的流量。通过计算吸引和排斥拉格朗日相干结构,可以进一步了解反流。对于各种等级的反流,观察到两个流入的射流及其剪切层卷起之间有趣的相互作用。这项研究突出了流动特征,这些流动特征可用于进一步评估反流严重程度。

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