• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Bulletin of the American Physical Society >APS -70th Annual Meeting of the APS Division of Fluid Dynamics- Event - Interfacial distribution of mucus under forced expiration in a double bifurcation model
【24h】

APS -70th Annual Meeting of the APS Division of Fluid Dynamics- Event - Interfacial distribution of mucus under forced expiration in a double bifurcation model

机译：APS-流体动力学APS部门第70届年会-事件-双分叉模型中强制呼入下粘液的界面分布

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Mucus is removed from the lung airways by the rhythmic beating of cilia and the mucus interaction with the turbulent core airflow generated during a cough or forced expiration. The quantity and quality of mucus are adversely altered, impairing mucociliary clearance under chronic pulmonary conditions. Existing studies on airflow induced mucus clearance have established a functional relationship between the airflow rate, mucus properties, flow bias, breathing frequency and clearance; however, the impact of airway branching, gravity, and characterization of primary and secondary flows have not been studied. The focus of the current investigation is the detailed understanding of air-mucus two-phase flow mechanism under steady expiratory airflow in a double bifurcation model. The effect of different airflow rates and mucus viscosities on the flow morphology, mucus layer thickness, mucus clearance and pressure drop across the model will be discussed. The impact of in-plane and out-of-plane configurations of the bifurcation model on the primary and secondary flow structures as well as the mucus distribution will be addressed. In addition, a detailed comparison of the flow structures in the mucus-lined airways, and its corresponding dry wall (no mucus lining) case will be presented.
机译：通过纤毛的有节奏的跳动，将粘液从肺气道中清除，并将粘液与咳嗽或强迫呼气期间产生的湍流核心气流相互作用。粘液的数量和质量受到不利影响，在慢性肺部条件下损害粘膜纤毛清除。现有的关于气流引起的粘液清除的研究已经在气流速率，粘液性质，流动偏向，呼吸频率和清除之间建立了功能关系。然而，尚未研究气道分支，重力和一次和二次流动特性的影响。当前研究的重点是在双分叉模型中详细了解稳定呼气气流下的气液两相流动机理。将讨论不同气流速率和粘液粘度对模型中流动形态，粘液层厚度，粘液清除率和压降的影响。将解决分叉模型的平面内和平面外配置对主要和次要流动结构以及黏液分布的影响。此外，将对衬有粘液的气道及其相应的干壁（无粘液衬里）情况的流动结构进行详细比较。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号