...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Scientific reports. >Association between levonorgestrel emergency contraception and the risk of ectopic pregnancy: a multicenter case-control study
【24h】

Association between levonorgestrel emergency contraception and the risk of ectopic pregnancy: a multicenter case-control study

机译：左炔诺孕酮紧急避孕药与异位妊娠风险之间的关联：多中心病例对照研究

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cases of ectopic pregnancy (EP) following levonorgestrel emergency contraception (LNG-EC) failure have been reported continuously, but whether there is an association between EP risk and LNG-EC is unclear. We concluded a case-control study to explore this association by recruiting 2,411 EP patients as case group, and 2,416 women with intrauterine pregnancy and 2,419 non-pregnant women as control groups. Odds ratios (ORs) and their 95% confidential intervals (CIs) were calculated and adjusted for potential confounding factors. Previous use of LNG-EC was not correlated with the EP. Compared to women who did not use contraceptives, current use of LNG-EC reduced the risk for intrauterine pregnancy (Adjusted OR [AOR] = 0.20, 95%CI: 0.14–0.27), but did not increase the risk for EP (AOR2 = 1.04, 95%CI: 0.76–1.42). Furthermore, compared to women who did not have further act of intercourse, women with unprotected further act of intercourse were at a higher risk of EP (AOR1 = 2.35, 95%CI: 1.17–4.71), and women with repeated use of LNG-EC for further intercourse during the same cycle was also associated with a higher risk for EP (AOR1 = 3.08, 95%CI: 1.09–8.71; AOR2 = 2.49, 95%CI: 1.00–6.19). A better understanding of the risk of EP following LNG-EC failure can optimize LNG-EC use and thus reduce the risk of EP.
机译：左炔诺孕酮紧急避孕（LNG-EC）失败后发生异位妊娠（EP）的病例不断报道，但尚不清楚EP风险与LNG-EC之间是否存在关联。我们结束了一项病例对照研究，通过招募2,411名EP患者作为病例组，2,416名宫内妊娠妇女和2,419名非妊娠妇女作为对照组来探索这种关联。计算赔率（OR）及其95％的机密区间（CI），并针对潜在的混杂因素进行调整。 LNG-EC的先前使用与EP无关。与不使用避孕药的妇女相比，目前使用LNG-EC可以降低宫内妊娠的风险（校正OR [AOR] = 0.20，95％CI：0.14-0.27），但并没有增加EP的风险（AOR < sub> 2 = 1.04，95％CI：0.76-1.42）。此外，与没有进一步性交行为的女性相比，没有保护性性交行为的女性发生EP的风险更高（AOR 1 = 2.35，95％CI：1.17–4.71），并且在同一周期内反复使用LNG-EC进行进一步性交的女性也有较高的EP风险（AOR 1 = 3.08，95％CI：1.09–8.71; AOR 2 = 2.49，95％CI：1.00–6.19）。更好地了解LNG-EC失效后的EP风险可以优化LNG-EC的使用，从而降低EP的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号