...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Scientific reports. >Quantitative Analysis of Inflammation in Orbital Fat of Thyroid-associated Ophthalmopathy Using MRI Signal Intensity
【24h】

Quantitative Analysis of Inflammation in Orbital Fat of Thyroid-associated Ophthalmopathy Using MRI Signal Intensity

机译：利用MRI信号强度定量分析甲状腺相关性眼病眼眶脂肪中的炎症

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We quantitatively analyzed inflammation in orbital fat from cases of thyroid-associated ophthalmopathy (TAO) using short-tau inversion recovery (STIR) sequences from magnetic resonance imaging. The signal intensity ratios (SIRs) of orbital fat as well as the superior rectus (SR), inferior rectus (IR), lateral rectus (LR), medial rectus (MR), and superior oblique (SO) muscles on STIR images were measured in 70 eyes from 70 treatment-naive TAO patients (active TAO group, 19 patients; inactive TAO group, 51 patients) and 20 eyes from 20 controls. The mean SIR in the active TAO group was significantly higher than that in the inactive TAO group and controls (P??0.001). The SIR of orbital fat in all TAO patients was significantly (P??0.001) positively correlated with that of the extraocular muscles: SR (r?=?0.64), IR (r?=?0.55), LR (r?=?0.58), MR (r?=?0.71), and SO (r?=?0.65). The SIR of orbital fat had a significant positive correlation with the CAS (r?=?0.53, P??0.001). The measurements of SIRs in orbital fat may be useful in evaluating the activity in tissues of TAO patients.
机译：我们使用磁共振成像的短头倒置恢复（STIR）序列定量分析了甲状腺相关性眼病（TAO）病例的眼眶脂肪中的炎症。测量了STIR图像上眶脂肪以及上直肌（SR），下直肌（IR），外侧直肌（LR），内侧直肌（MR）和上斜肌（SO）的信号强度比（SIR） 70例未接受过治疗的TAO患者中有70眼（活动性TAO组19例;非活动性TAO组51例）和20例对照的20眼。活跃的TAO组的平均SIR显着高于不活跃的TAO组和对照组（P <0.001）。所有TAO患者的眼眶脂肪的SIR与眼外肌的SIR呈显着正相关（P <0.001），SR（r = 0.64），IR（r = 0.55），LR（r ==）。 （0.58），MR（r ＝ 0.71）和SO（r ＝ 0.65）。眼眶脂肪的SIR与CAS呈显着正相关（r≥0.53，P <0.001）。眼眶脂肪中SIR的测量可能有助于评估TAO患者组织中的活性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号