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首页> 外文期刊>Scientific reports. >Effect of intravitreal or sub-tenon triamcinolone acetonide injection at completion of vitrectomy on peripheral retinochoroidal thickness in eyes with proliferative diabetic retinopathy
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Effect of intravitreal or sub-tenon triamcinolone acetonide injection at completion of vitrectomy on peripheral retinochoroidal thickness in eyes with proliferative diabetic retinopathy

机译：玻璃体切除术完成后玻璃体内或肌腱下注射醋酸曲安奈德对增生性糖尿病性视网膜病变的眼睛周围脉络膜脉络膜厚度的影响

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The effect of triamcinolone acetonide (TA) on the peripheral retinochoroidal thickness was determined after pars plana vitrectomy (PPV) with scatter photocoagulation in eyes with proliferative diabetic retinopathy. The peripheral retinochoroidal thickness was measured at 5?mm from the limbus in the four quadrants using anterior segment optical coherence tomography before, and 3 days, and 1 and 2 weeks after the surgery. The total peripheral thickness was significantly thicker than the baseline thickness after PPV alone (P??0.001; 18 eyes), PPV combined with intravitreal TA injection (IVTA; P?=?0.011; 19 eyes), and PPV combined with sub-tenon TA injection (STTA; P?=?0001; 23 eyes). The total peripheral thickness in the PPV group at 3 days after surgery was significantly thicker than that of the PPV?+?IVTA (P?=?0.015) and of the PPV?+?STTA groups (P?=?0.016). Multiple linear regression analyses showed that the injection of TA by the two routes and the number of photocoagulation burns were significantly correlated with the total peripheral thicknesses at 3 days after the surgery. The results indicate that the PPV with large number of intraoperative scatter photocoagulation burns caused an increase in the total peripheral thickness and an administration of either IVTA and STTA can reduced the degree of thickening.
机译：在患有增生性糖尿病性视网膜病变的眼睛中，经pars平板玻璃体切除术（PPV）散射光凝后，测定曲安奈德（TA）对周围视网膜脉络膜厚度的影响。术前，术后3天，术后1和2周，使用前节光学相干断层扫描在四个象限距角膜缘5？mm处测量外周脉络膜厚度。在单独PPV（P 0.001; 18眼），PPV联合玻璃体内TA注射（IVTA; P <= 0.011; 19眼）和PPV与亚组联合治疗后，总外周厚度显着大于基线厚度。肌腱TA注射（STTA; P？=？0001; 23眼）。术后3天PPV组的总外周厚度明显大于PPVα+ΔIVTA组（Pα＝Δ0.015）和PPVβ+ΔSTTA组（Pα＝Δ0.016）。多元线性回归分析表明，两种途径的TA注射和光凝烧伤次数与术后3天的总外周厚度显着相关。结果表明，术中散布大量光凝性烧伤的PPV导致总外周厚度增加，同时给予IVTA和STTA均可降低增厚程度。

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