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Survival analysis of adult and children intermittent exotropia using a matched case-control design

机译：匹配病例对照设计的成人和儿童间歇性外斜视生存分析

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To compare the surgical outcomes of adult intermittent exotropia (X(T)) patients and matched control children X(T) patients including survival analysis. Fifty-two adult X(T) patients and 129 matched control children X(T) patients were included. Clinical characteristics, survival analysis, and surgical dose-response curves were evaluated and compared between the two groups. The weighted Cox proportional hazards regression analysis was used in order to find risk factors for the recurrence. Using Kaplan-Meier survival analysis, the cumulative probability of survival rate considering recurrence as event of Adult group were 93.97% for one year, and maintained at 88.44% for two, three. four, and five years after surgery. In contrast, those of the Child group were 83.6%, 76.5%, 65.6%, 56.23%, and 40.16% for one, two, three, four, and five years after surgery, respectively. The Adult group had a better event-free survival curve than the Child group as analyzed by a Log-rank test (p?=?0.020). According to multivariate weighted Cox regression analysis, the younger age at operation and the larger preoperative angle were significant risk factors for recurrence.
机译：为了比较成人间歇性外斜视（X（T））患者和相匹配的对照儿童X（T）患者的手术结局，包括生存分析。包括52名成人X（T）患者和129名匹配的对照儿童X（T）患者。评价两组的临床特征，生存分析和手术剂量反应曲线，并进行比较。为了找到复发的危险因素，使用了加权Cox比例风险回归分析。使用Kaplan-Meier生存分析，将成年组复发视为事件的生存率的累积概率一年为93.97％，而二，三年维持在88.44％。手术后四年和五年。相比之下，Child组在术后1年，2年，3年，4年和5年分别为83.6％，76.5％，65.6％，56.23％和40.16％。通过对数秩检验分析，成人组比儿童组有更好的无事件生存曲线（p？=？0.020）。根据多元加权Cox回归分析，手术年龄较小和术前角较大是复发的重要危险因素。

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