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Genome Scale Identification of Treponema pallidum Antigens

机译:基因氨酸Pallidum抗原的基因组尺度鉴定

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Antibody responses for 882 of the 1,039 proteins in the proteome of Treponema pallidum were examined. Sera collected from infected rabbits were used to systematically identify 106 antigenic proteins, including 22 previously identified antigens and 84 novel antigens. Additionally, sera collected from rabbits throughout the course of infection demonstrated a progression in the breadth and intensity of humoral immunoreactivity against a representative panel of T. pallidum antigens.
机译:检查了在 Treponema Pallidum 蛋白质组中的882个蛋白质中的882件的抗体反应。从感染的兔子收集的血清用于系统地鉴定106个抗原蛋白,其中包括22例先前鉴定的抗原和84个新的抗原。此外,在整个感染过程中从兔子收集的血清表现出对 T的代表面板的体液免疫反应性的宽度和强度。 Pallidum 抗原。

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