Enhancement of Primary Antigen-Specific Resistance in Infant Mice with Divinyl Ether-Maleic Anhydride

J. Y. Richmond; C. H. Campbell

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Enhancement of Primary Antigen-Specific Resistance in Infant Mice with Divinyl Ether-Maleic Anhydride

机译：二乙醚 - 马来酸酐幼儿小鼠初级抗原特异性抗性的提高

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The early response of infant mice to foot-and-mouth disease viral antigens, measured by greater resistance and increased serum-neutralizing antibody, was enhanced by divinyl ether-maleic anhydride (DVE/MA). Preparations of known antigen concentration were used to study various parameters influencing this enhancement. Resistance and antibody levels were increased when DVE/MA was administered with aqueous or oil-emulsified antigens, whether given separately or mixed with the antigens, but was dependent on the dose and route of the DVE/MA and antigen. Enhanced resistance developed rapidly, was antigen-specific, and may have been related to the level of neutralizing antibody.

机译：通过二乙醚 - 马来酸酐（DVE / MA）增强了通过更大的抗性和增加的血清中和抗体测量的婴幼儿小鼠对口蹄疫病毒抗原的早期反应。使用已知抗原浓度的制剂用于研究影响这种增强的各种参数。当用水性或油乳化抗原给予DVE / MA时，抗性和抗体水平增加，无论是否与抗原单独或混合，而是依赖于DVE / MA和抗原的剂量和途径。增强的抗性迅速发展，是抗原特异性的，并且可能与中和抗体水平有关。

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《Infection and immunity》 |1974年第5期|共5页
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J. Y. Richmond; C. H. Campbell;
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6. Enhancement of Primary Antigen-Specific Resistance in Infant Mice with Divinyl Ether-Maleic Anhydride [O] . J. Y. Richmond, C. H. Campbell 1974

机译：二乙烯基醚-顺丁烯二酸酐增强婴儿小鼠初级抗原特异性抗性
7. Interleukin-5 Transgenic Mice Show Enhanced Resistance to Primary Infections with Nippostrongylus brasiliensis but Not Primary Infections with Toxocara canis [O] . Lindsay A. Dent, Christine M. Daly, Graham Mayrhofer, 1999

机译：白细胞介素-5转基因小鼠表现出对Nippostrongylus Brasiliensis的原发性感染的抗性增强，但没有用毒素犬的原发性感染

Enhancement of Primary Antigen-Specific Resistance in Infant Mice with Divinyl Ether-Maleic Anhydride

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