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首页> 外文期刊>BMC Cardiovascular Disorders >A cardiovascular disease risk factor in children with congenital heart disease: unmasking elevated waist circumference - a CHAMPS* study *CHAMPS: Children’s Healthy-Heart Activity Monitoring Program in Saskatchewan
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A cardiovascular disease risk factor in children with congenital heart disease: unmasking elevated waist circumference - a CHAMPS* study *CHAMPS: Children’s Healthy-Heart Activity Monitoring Program in Saskatchewan

机译：先天性心脏病儿童心血管疾病危险因素：揭开腰围升高的腰围 - 香榭丽舍*冠军：萨斯喀彻温省儿童健康 - 心脏活动监测计划

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Children with congenital heart disease (CHD) have an elevated risk of future cardiovascular disease but the underlying mechanisms are unclear. Abdominal obesity (measured as waist circumference) is a risk factor for adult onset of cardiovascular diseases and is correlated with low physical activity levels, commonly found in children with congenital heart disease. Elevated waist circumference may be a mechanism by which cardiovascular disease risk is elevated in children with CHD. The purpose of this study was to compare waist circumference between children with and without CHD, while considering potential confounders. We hypothesized that children with CHD would have higher measures of waist circumference when controlling for differences in birthweight, lean mass, and physical activity. Thirty-two children with CHD (10.9?±?2.6?years; 12 female) from the Children’s Healthy-Heart Activity Monitoring Program in Saskatchewan, and 23 healthy controls (11.7?±?2.5?years; 10 female) were studied. Waist circumference, physical activity (physical activity questionnaire), body composition (lean mass; dual x-ray absorptiometry), and birthweight were assessed. Analysis of covariance, Mann-Whitney U, and independent sample t-tests were used to assess group differences (p 0.05). Our findings generate a novel hypothesis—higher waist circumferences in children with CHD compared to age-matched controls, may contribute to an elevated risk of cardiovascular disease.
机译：具有先天性心脏病（CHD）的儿童具有未来心血管疾病的风险升高，但潜在的机制尚不清楚。腹部肥胖（测量为腰围）是成年心血管疾病发病的危险因素，并且与具有先天性心脏病的儿童常见的低体育活动水平相关。腰围升高可能是CHD患儿心血管疾病风险的机制。本研究的目的是在考虑潜在的混乱时比较有和没有CHD的儿童之间的腰围。我们假设CHD的儿童在控制出生体重，精益质量和身体活动的差异时具有更高的腰围措施。来自萨斯喀彻温省儿童健康心脏活动监测计划的儿童健康 - 心脏活动监测计划的32名儿童（10.9？±2.6岁），研究了23例健康控制（11.7？±2.5​​？岁; 10岁; 10雌性）。腰围，身体活动（身体活动问卷），身体成分（贫质量;双X射线吸收测定法）和出生体重。用于评估组差异的协方差，Mann-Whitney U和独立样品T检验分析（P 0.05）。与年龄匹配的对照相比，我们的研究结果在CHD的儿童中产生了一种新的假设腰周围，可能有助于心血管疾病的危险升高。

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