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Lenticular fungal infection caused by Aspergillus in a patient with traumatic corneal laceration: a case report

机译:由创伤性角膜撕裂患者患者引起的晶二酚真菌感染:案例报告

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To report a case of lenticular infection caused by Aspergillus, which was diagnosed 13?weeks after traumatic corneal laceration. A 60-year-old woman presented with traumatic corneal laceration including anterior lens capsule rupture and traumatic cataract after being hit with a chestnut in the right eye. There were multiple injuries due to tiny thorns of the chestnut, including the conjunctiva, sclera, cornea, and anterior lens capsule. But no visible foreign body was detected by slit-lamp examination. Topical corticosteroid was prescribed to resolve the conjunctival inflammation induced by the thorns of chestnut, which could have caused persistent irritation. As conjunctival injection and edema being decreased during outpatient clinical follow-up, embedded conjunctival foreign body was detected and surgically removed (1st surgery). Approximately 10 weeks after the trauma, severe inflammation of the anterior segment accompanied with hypopyon developed suddenly and at the same time embedded scleral foreign body was revealed. After removal of scleral foreign body (2nd surgery), unspecified mold species was cultured from the scleral foreign body in SDA (Sabouraud dextrose agar) plate. Suspicious corneal foreign body was removed as 3rd surgery and phacoemulsification of traumatic cataract was planned as 4th surgery. Aspergillus was finally detected from removed anterior capsule and fibrotic membrane during the operation. Fungal infection resolved successfully after administration of topical (1% voriconazole and 5% natamycin) and systemic (fluconazole) antifungal agents and phacoemulsification of traumatic cataract. Chestnut thorns can damage multiple ocular tissues simultaneously. Lens capsular rupture could result in fungal inoculation and lead to delayed lenticular fungal infection with complicated cataract formation. In cases of ocular trauma due to organic substances such as thorns and branches, the possibility of fungal infection should be considered.
机译:报告由曲霉引起的晶瓣感染的情况,该病例被诊断为13〜3周后创伤性角膜撕裂。一名60岁的女性呈现出创伤性角膜撕裂,包括前镜头囊破裂和创伤性白内障后,右眼栗子击中后。由于栗子的微小荆棘,包括结膜,巩膜,角膜和前镜头胶囊,有多次伤害。但是,狭缝灯检查没有检测到可见的异物。规定局部皮质类固醇以解决栗子荆棘引起的结膜炎,这可能导致持续的刺激。作为在门诊临床随访期间的结膜注射和水肿,嵌入式结膜异物被检测到并手术移除(第一次手术)。在创伤后大约10周,伴随着突然间,伴随着胚胎外部体内的前段伴有的前段的严重炎症。除去巩膜异物(第二次手术)后,在SDA(Sabourauct右旋糖糖浆)板中从巩膜异物中培养未指定的模子。可疑角膜异物被移除为第3次手术,创伤性白内障的沉重乳化被计划为第4手术。在操作期间最终从去除的前囊和纤维化膜中检测到曲霉。真菌感染在局部(1%voriconazole和5%NaTamycin)和全身(氟康唑)抗真菌剂和创伤性白内障的沉淀后成功解决。栗子刺可以同时损伤多个眼组织。镜片囊破裂可能导致真菌接种并导致延迟晶二酚的真菌感染复杂的白内障地层。在由于有机物质(如刺和分支)导致的眼外伤的情况下,应考虑真菌感染的可能性。

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