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首页> 外文期刊>BMC Ophthalmology >Grading of macular perfusion in retinal vein occlusion using en-face swept-source optical coherence tomography angiography: a retrospective observational case series
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Grading of macular perfusion in retinal vein occlusion using en-face swept-source optical coherence tomography angiography: a retrospective observational case series

机译：使用嵌入扫描源光学相干断层造影血管造影的视网膜静脉闭塞性黄斑灌注分级：回顾性观察案例系列

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To evaluate the efficacy of swept -source optical coherence tomography angiography (SS-OCTA) in grading macular perfusion in retinal vein occlusion. Retrospective observational case series including patients with different types of retinal vein occlusion (RVO). SS-OCTA utilizes OCTARA algorithm to examine the retinal vascular plexuses for the presence of morphological signs of ischemia according to a predetermined grading scheme. The findings were compared with fundus fluorescein angiography (FFA), and swept-source optical coherence tomography (SS-OCT) features. Bivariate correlation, coefficient of determination, and crosstabs procedures were used to calculate inter-variable linear correlation, relative contribution of the tested variables, and multivariate association, respectively. The study included 144 eyes of 138 patients. The most common type of RVO was branch retinal vein occlusion (BRVO) (53%). The superficial capillary plexus (SCP) and the deep capillary plexus (DCP) did not correlate with each other in all parameters tested. Increased central macular thickness (CMT) and disrupted retinal outer layers (DROL) were associated with increased severity of ischemia in DCP. Disorganized retinal inner layers (DRIL) correlated significantly with the presence of perifoveal capillary ischemia in the SCP and the DCP. Macular ischemia on FFA correlated with ischemia in the SCP layer only. Increased CMT, DROL and DRIL on SS-OCT, and SCP and DCP ischemia on SS-OCTA contributed significantly to diminished best-corrected visual acuity (BCVA). SS-OCTA is more precise in?defining?the extent and location of maximum ischemic insult following RVO compared to FFA, hence represents a more efficient grader for ischemic damage in the posterior pole. Increased CMT, DRIL, and DROL on SS-OCT, and SCP and DCP ischemia on SS-OCTA are significant predictors of poor visual outcome.
机译：评价扫掠 - 源光学相干断层造影血管造影（SS-Octa）在视网膜静脉闭塞中分级黄斑灌注中的功效。回顾性观察盒系列包括不同类型的视网膜静脉闭塞（RVO）的患者。 SS-Octa利用octarA算法检查视网膜血管丛，用于根据预定的分级方案检查缺血的形态素迹象。将研究结果与眼底荧光血管造影（FFA）进行比较，以及扫描源光学相干断层扫描（SS-OCT）特征。双变量相关性，测定系数和克罗斯杆菌程序分别用于计算可变的线性相关性，测试变量的相对贡献和多变量关联。该研究包括138名患者144只眼睛。最常见的RVO类型是分支视网膜静脉闭塞（BRVO）（53％）。浅表毛细血管丛（SCP）和深毛细血管丛（DCP）在测试的所有参数中彼此不相关。增加中央黄斑厚度（CMT）和破坏的视网膜外层（DROL）与DCP中缺血的严重程度增加相关。在SCP和DCP中存在骨膜毛细血管缺血的存在显着相关性的视网膜内层（DRIL）。对FFA的黄斑缺血仅与SCP层中的缺血相关。在SS-OCT上增加CMT，DROL和DRIL，SS-OCTA上的SCP和DCP缺血显着贡献，以减少最佳校正的视力（BCVA）。 SS-Octa更精确？定义？与FFA相比，RVO在RVO相比，最大缺血性侮辱的程度和位置，因此代表了在后极缺血损伤的更有效的成绩。 SS-OCT上的CMT，DRIL和DROL增加，SS-OCTA上的SCP和DCP缺血是视觉结果不佳的重要预测因子。

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