• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Ophthalmology >Human adenoviral type 54 keratoconjunctivitis accompanied by stellate keratitis and keratic precipitates: two cases
【24h】

Human adenoviral type 54 keratoconjunctivitis accompanied by stellate keratitis and keratic precipitates: two cases

机译：人体腺病毒型54个角膜炎症伴有星状角膜炎和颈椎沉淀物：两种情况

获取原文
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Of the 10 patients with adenoviral type 54 keratoconjunctivitis examined at Nojima Hospital, 2 developed stellate keratitis and mutton-fat keratic precipitates (KPs) following acute symptoms. We encountered 10 cases of epidemic keratoconjunctivitis from August to October 2017. All patients were adults with a mean age of 60.9?±?10.0?years. The species D human adenovirus (HAdV)-54 was detected in the conjunctival scrapings of these patients. Fluorometholone instillation was administered during the first week for acute symptomatic relief. Case 1: A 64-year-old female was prescribed with fluorometholone instillation, which was discontinued after 1?week when her symptoms alleviated. One week after discontinuation of the instillation, she presented with blurred vision in her left eye with KPs and multiple stellate keratitis. The anterior chamber had no apparent cells. Her symptoms disappeared after 1?week of betamethasone instillation. Case 2: A 66-year-old female was prescribed with 0.1% fluorometholone instillation, which was discontinued within10 days. Three months after the appearance of initial symptoms, multiple subepithelial corneal infiltrates (MSI) appeared in her eyes. Stellate keratitis and dark-brown pigmentation were observed in the centres of MSI, with several cells in the anterior chamber. Betamethasone was prescribed, and MSI and stellate keratitis improved within 1?week. However, KPs were observed in the left eye. The instillation was continued for 3 more weeks until symptoms improved. MSI is an immune reaction that occurs after the disappearance of acute symptoms. Here, corneal findings and KPs were observed after improvement in eye redness and discontinuation of steroids. These symptoms were presumed to be secondary inflammation due to immune response to the adenoviral antigen. The clinical features of HAdV-54 keratoconjunctivitis on the ocular surface are initially moderate, but become active in the subacute to chronic phases. This may develop atypical findings, including stellate keratitis with KPs. Although early steroid administration can relieve acute symptoms, it may facilitate chronic corneal immunological reaction.
机译：在Nojima医院检查的10例腺病毒型54患者中，2次出现的星状角膜炎和羊皮静脉沉淀物（KPS）后急性症状。我们遇到了从2017年8月到10月遇到的10例流行病角膜炎炎。所有患者都是平均年龄为60.9的成年人？±10.0？年。在这些患者的结膜刮擦中检测到物种D人腺病毒（HADV）-54。急性症状缓解的第一周施用氟塞勒酮滴注。案例1：一名64岁的女性被氟塞勒龙滴注在一起，在她的症状减轻后1个星期后停止。停止滴注后一周，她用KPS和多个星状角膜炎的左眼显示了模糊的视觉。前房没有明显的细胞。在1？一周的倍虫松滴注后，她的症状消失了。案例2：66岁的女性含有0.1％的氟塞勒龙滴注，在10天内停产。在初始症状外观后三个月，在她的眼中出现了多种耻骨上的角膜渗透（MSI）。在MSI的中心中观察到星状角膜炎和深棕色色素沉着，在前室中有几个细胞。漂败的塞米松被规定，MSI和星状角膜炎在1？周内改善。然而，在左眼中观察到KPS。滴注持续3周，直至症状改善。 MSI是一种免疫反应，在急性症状消失后发生。在这里，在改善眼睛发红和类固醇后观察到角膜发现和KPS。由于免疫应答对腺病毒抗原的免疫应答，这些症状被认为是次生炎症。 Hadv-54角膜炎眼性肝炎患者在眼表面上的临床特征最初是中等的，但在慢性阶段的亚次急性中活跃。这可能会制定非典型发现，包括具有KPS的星状角膜炎。虽然早期类固醇给药可以缓解急性症状，但它可能促进慢性角膜免疫反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号