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Patterns of uveitis in children according to age: comparison of visual outcomes and complications in a tertiary center

机译:儿童葡萄膜炎的模式:在第三中心的视觉结果和并发症的比较

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Uveitis in the pediatric population is uncommon, accounting for 2 to 14% of all uveitis cases, yet resulting in significant ocular morbidity. A number of studies have focused on patterns and complications of uveitis in the pediatric age group (≤ 16?years). In this report, we studied children with uveitis syndromes focusing on demographics, anatomic distribution, etiologies, treatment, and complications. We additionally divided subjects into two age groups to look into any differential characteristics pertaining to the younger age group and the role of amblyopia as a cause of visual loss. Retrospective chart review of 80 eyes of 49 uveitis patients aged ≤16?years. Subjects were categorized by age of onset into visually immature (≤8?years) and visually mature group (?8?years). Data compared between the two age groups included demographics, disease characteristics, visual outcomes and complications. Idiopathic uveitis was the most common diagnosis (51%). Anterior uveitis complications (posterior synechiae and band keratopathy) were more common in the younger group (p?=?0.002 and p?=?0.03 respectively) while posterior uveitis manifestations (vitreous haze and vasculitis) were more common in the older age group (p?=?0.04 and p??0.001 respectively). Amblyopia was the most common cause of vision loss in the visually immature versus cataract in the visually mature. Anterior uveitis and its complications were more common in visually immature group in our cohort. Amblyopia was identified as the main cause of visual loss in the younger population.
机译:儿科人口中的葡萄膜炎是罕见的,占所有葡萄膜炎病例的2%至14%,但导致了显着的眼镜发病率。许多研究专注于儿科年龄组(≤16?年)在儿科年龄组中的葡萄膜炎的模式和并发症。在本报告中,我们研究了患有葡萄膜炎综合征,重点的葡萄膜炎综合征,解剖分布,病因,治疗和并发症。我们另外将受试者分为两个年龄组,以研究与年龄组有关的任何差异特征,以及弱视作为视觉损失原因的作用。回顾性图表审查80只49岁患者的80只眼睛≤16岁?年。受试者通过发病年龄分类为视觉上的未成熟(≤8Ω·年)和视觉上成熟组(>?8?年)。两年龄段之间的数据包括人口统计学,疾病特征,视觉结果和并发症。特发性葡萄膜炎是最常见的诊断(51%)。在较年轻的群体(P?= 0.002和P≤0.002和p​​≤0.03)中,前u病例并发症(后闭合和角膜病变)更常见(分别为0.002和p​​≤0.03),而在较旧的年龄组中更常见(玻璃体雾霾和血管炎)( p?= 0.04和p?<0.001分别)。弱视是视觉上未成熟的视觉损失最常见的视觉损失原因。前葡萄膜炎及其并发症在队列的视觉未成熟组中更常见。弱视被确定为年幼人口视力损失的主要原因。

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