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首页> 外文期刊>BMC Ophthalmology >The repeatability of superficial retinal vessel density measurements in eyes with long axial length using optical coherence tomography angiography
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The repeatability of superficial retinal vessel density measurements in eyes with long axial length using optical coherence tomography angiography

机译：光学相干断层造影血管造影长度轴长浅表视网膜密度测量的可重复性

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To investigate the repeatability of superficial retinal vessel density measurements in healthy eyes with long axial length (AL) using optical coherence tomography angiography (OCTA). There were 60 eyes of 31 volunteers enrolled in this cross-sectional observational study. All subjects underwent OCTA, AL and refraction test. The enrolled eyes were divided into the long AL group (26?mm?≤?AL??28?mm) and normal AL group (22?mm?≤?AL??26?mm). The vessel length density (VLD), perfusion density (PD), and fovea avascular zone (FAZ) of the superficial retinal vessel were evaluated. Repeatability was assessed by intraclass correlation coefficients (ICCs) and Bland-Altman analysis. Pearson's r correlation was used to analyze the relation of AL and the absolute difference between two measurements. The 3?×?3?mm scan pattern showed good repeatability with all ICCs over 0.7. For all parameters of all scan patterns, the ICCs of the normal AL group were distinctly higher than those of the long AL group; this finding was also confirmed by Bland-Altman analysis. The correlation analysis of AL and repeatability of OCTA parameters showed significant negative correlations between the ALs and repeatability of VLD in 6?×?6?mm inner ring (r2?=?0.13, p?=?0.01), VLD in 6?×?6?mm outer ring (r2?=?0.09, p?=?0.02) and PD in 6?×?6?mm outer ring (r2?=?0.08, p?=?0.03). The AL and the scanned area will both affect the repeatability of superficial retinal vessel density measurements in OCTA.
机译：研究使用光学相干断层造影血管造影（OctA）的长轴长度（Al）具有长轴长度（Al）的健康眼中浅表视网膜密度测量的可重复性。在这个横断面观察研究中，有60只志愿者参加了31只志愿者。所有受试者都经历了Octa，Al和折射试验。将注册的眼睛分成长Al组（26Ω·mm？≤α≤α，α<α22mm）和普通Al组（22Ωmm≤≤≤≤≤α，<？26Ωmm）。评估血管长度密度（VLD），灌注密度（Pd）和浅表视网膜容器的血管血管区（FAZ）。通过脑内相关系数（ICC）和Bland-Altman分析评估重复性。 Pearson的R相关用于分析Al的关系和两次测量之间的绝对差异。 3？×3？mm扫描模式显示出良好的重复性，所有ICC超过0.7。对于所有扫描模式的所有参数，普通Al组的ICC明显高于Long Al组的ICC;这一发现也得到了Bland-Altman分析的确认。 Al的相关性分析和Octa参数的可重复性在6？×6？6？mm内环（R2？= 0.13，p≤0.13，p≤x0.13），6？××× ？6？mm外圈（R2？=Δ= 0.09，p？= 0.02）和Pd在6？×6？mm外圈（R2？= 0.08，p？= 0.03）。 Al和扫描区域会影响Octa中浅表视网膜血管密度测量的可重复性。

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