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首页> 外文期刊>BMC Endocrine Disorders >Obtaining evidence base for the development of Feel4Diabetes intervention to prevent type 2 diabetes – a narrative literature review
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Obtaining evidence base for the development of Feel4Diabetes intervention to prevent type 2 diabetes – a narrative literature review

机译：获取发育感受4年的干预以防止2型糖尿病的证据基础 - 叙事文献综述

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Feel4Diabetes was a school and community based intervention aiming to promote healthy lifestyle and tackle obesity for the prevention of type 2 diabetes among families in 6 European countries. We conducted this literature review in order to guide the development of evidence-based implementation of the Feel4Diabetes intervention. We focused on type 2 diabetes prevention strategies, including all the phases from risk identification to implementation and maintenance. Special focus was given to prevention among vulnerable groups and people under 45?years. Scientific and grey literature published between January 2000 and January 2015 was searched for relevant studies using electronic databases. To present the literature review findings in a systematic way, we used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework. A complementary literature search from February 2015 to December 2018 was also conducted. The initial review included 27 studies with a follow-up ≥12?months and 9 studies with a follow-up ≥6?months and with a participant mean age??45?years. We found out that interventions should be targeted at people at risk to improve recruiting and intervention effectiveness. Screening questionnaires (primarily Finnish Diabetes Risk Score FINDRISC) and blood glucose measurement can both be used for screening; the method does not appear to affect intervention effectiveness. Screening and recruitment is time-consuming, especially when targeting lower socioeconomic status and age under 45?years. The intervention intensity is more important for effectiveness than the mode of delivery. Moderate changes in several lifestyle habits lead to good intervention results. A minimum of 3-year follow-up seemed to be required to show a reduction in diabetes risk in high-risk individuals. In participants ?45?years, the achieved results in outcomes were less pronounced. The complementary review included 12 studies, with similar results regarding intervention targets and delivery modes, as well as clinical significance. This narrative review highlighted several important aspects that subsequently guided the development of the Feel4Diabetes high-risk intervention. Research on diabetes prevention interventions targeted at younger adults or vulnerable population groups is still relatively scarce. Feel4Diabetes is a good example of a project aiming to fill this research gap. clinicaltrials.gov NCT02393872, registered 20th March 2015.
机译：感觉4年的疫苗是一所学校和社区干预，旨在促进健康的生活方式，并在6个欧洲国家的家庭中预防2型糖尿病的肥胖。我们进行了这篇文献综述，以指导发展循证实施的肌肉疫苗干预。我们专注于2型糖尿病预防策略，包括从风险识别到实施和维护的所有阶段。特别重点是预防弱势群体和45岁以下的人。在2000年1月至2015年1月出版的科学和灰色文学被搜查了使用电子数据库的相关研究。要以系统的方式展示文献综述结果，我们使用了覆盖，有效性，采用，实施和维护（重新瞄准）框架。还开展了2015年2月至2018年12月的互补文献搜索。初步审查包括27项研究，随访≥12个月和9个研究，随访≥6？几个月，参与者意味着年龄？<？45？年。我们发现干预措施应该针对有风险的人，以提高招聘和干预效果。筛查问卷（主要是芬兰糖尿病风险得分FindRisc）和血糖测量都可以用于筛选;该方法似乎不会影响干预效果。筛选和招聘是耗时的，特别是在瞄准较低的社会经济地位和45岁以下的年龄时。干预强度对于效率比交付方式更重要。几种生活习惯的适度变化导致干预结果良好。至少需要3年的随访似乎需要在高危人员中表现出糖尿病风险的降低。在参与者中<45？年，结果的结果不太明显。互补综述包括12项研究，在干预目标和交付模式以及临床意义上具有类似的结果。这一叙述审查强调了几个重要方面，随后引导了感受4迪亚特高风险干预的发展。针对年轻成人或弱势群体群体的糖尿病预防干预措施仍然相对稀缺。感觉4迪亚特是一个旨在填补这项研究差距的项目的一个很好的例子。 ClinicalTrials.gov NCT02393872，2015年3月20日注册。

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