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Clinical indicators to identify neuropathic pain in low back related leg pain: a modified Delphi study

机译:临床指标,以鉴定低背关腿疼痛的神经性疼痛:改良的德尔福研究

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Neuropathic pain (NP) is common in patients presenting with low back related leg pain. Accurate diagnosis of NP is fundamental to ensure appropriate intervention. In the absence of a clear gold standard, expert opinion provides a useful methodology to progress research and clinical practice. The aim of this study was to achieve expert consensus on a list of clinical indicators to identify NP in low back related leg pain. A modified Delphi method consisting of three rounds was designed in accordance with the Conducting and Reporting Delphi Studies recommendations. Recruitment involved contacting experts directly and through expressions of interest on social media. Experts were identified using pre-defined eligibility criteria. Priori consensus criteria were defined for each round through descriptive statistics. Following completion of round 3 a list of clinical indicators that achieved consensus were generated. Thirty-eight participants were recruited across 11 countries. Thirty-five participants completed round 1 (92.1%), 32 (84.2%) round 2 and 30 (78.9%) round 3. Round 1 identified consensus (Kendall’s W coefficient of concordance 0.456; p??0.001) for 10 clinical indicators out of the original 14, and 9 additional indicators were added to round 2 following content analysis of qualitative data. Round 2 identified consensus (Kendall’s W coefficient of concordance 0.749; p??0.001) for 10 clinical indicators out of 19, and 1 additional indicator was added to round 3. Round 3 identified consensus for 8 indicators (Kendall’s W coefficient of concordance 0.648; p??0.001). Following completion of the third round, an expert derived consensus list of 8 items was generated. Two indicators; pain variously described a burning, electric shock like and/or shooting into leg and pain in association with other neurological symptoms (e.g. pins and needles, numbness, weakness), were found to have complete agreement amongst expert participants. Good agreement was found for the consensus derived list of 8 clinical indicators to identify NP in low back related leg pain. This list of indicators provide some indication of the criteria upon which clinicians can identify a NP component to low back related leg pain; further research is needed for stronger recommendations to be made.
机译:神经疗法疼痛(NP)在患有低相关腿部疼痛的患者中是常见的。确保适当干预的准确诊断NP是基本的。在没有明确的黄金标准的情况下,专家意见提供了进展和临床实践的有用方法。本研究的目的是在临床指标清单上实现专家共识,以识别低背关相关的腿部疼痛的NP。由三轮组成的改进的Delphi方法是根据拨进和报告Delphi研究建议设计的。招聘涉及直接与专家联系,通过对社交媒体的兴趣表达。使用预定义的资格标准确定专家。通过描述性统计数据为每轮定义先验的共识标准。完成第3轮完成后,产生了达成共识的临床指标清单。在11个国家招募了三十八名参与者。三十五名参与者完成第1轮(92.1%),32次(84.2%)第2轮和30次(78.9%)第3轮3.第1轮确定的共识(KENDALL的W系数0.456; p?<0.001)10个临床指标在原始14中,在定性数据的内容分析后,将9个另外的指标添加到第2轮。第2轮确定的共识(KENDALL的一系列临床指标的临床指标0.749; p?<0.001),并将另外1个另外的指标加入到第3轮中。第3轮确定8个指标(KENDALL的CONECORDING系数0.648 ; p?<?0.001)。完成第三轮后,产生了8项的专家派生共识清单。两个指标;疼痛各种各样地描述了燃烧,电击等和/或射击到腿部和与其他神经系统症状相关的疼痛(例如引脚和针头,麻木,弱点),在专家参与者之间有完整的协议。找到了8个临床指标的共识衍生列表的良好协议,以识别低背带相关腿部疼痛的NP。该指标清单提供了一些指示临床医生可以将NP组件识别到低背腿疼痛的标准;需要进一步研究,以便更强大的建议。

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