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首页> 外文期刊>BMC Nephrology >Evaluation of the chemical composition of nephrolithiasis using dual-energy CT in Southern Chinese gout patients
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Evaluation of the chemical composition of nephrolithiasis using dual-energy CT in Southern Chinese gout patients

机译：南方呼出患者双能CT评价肾状二病原的化学成分

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A study to evaluate the prevalence of uric acid (UA) nephrolithiasis with dual-energy CT (DECT) and explore the risk factors for kidney stones in primary gout patients. Eighty-four consecutive gout patients underwent urinary tract ultrasonography or DECT to confirm the existence of kidney stones. Urine and blood samples were also taken for laboratory analysis. Forty-one subjects (48.8%) had nephrolithiasis diagnosed; 38 had a kidney stone. Thirty-two of the 38 patients underwent a DECT scan, and 27 patients had nephrolithiasis in DECT. Among them, 63.0% (17/27) and 14.8% (4/21) of the patients had pure UA and UA-based mixed stone, respectively, and 22.2% (6/27) had a non-UA stone. Those with nephrolithiasis suffered from more frequent acute attacks and had longer disease durations of gout. At least one urine biochemical abnormality was found in 81% of patients. Forty-four (55.0%) patients presented hypomagnesuria. Forty-three (51.8%) patients had low urine volume. Unduly acidic urine (UAU) was present in 36 patients (44.4%). Hyperuricosuria was only found in ten (12.2%) patients. In comparison to the non-lithiasic group, the lithiasic group was more likely to have a UAU. Binary logistic regression showed that female gender was a protective factor, while disease duration of gout and low urine pH were risk factors for nephrolithiasis. Our results indicated that nephrolithiasis, especially UA stones, were more common than previous reports in gout patients indicated, and that disease duration of gout, and low urine pH, were risk factors for nephrolithiasis.
机译：评估双能CT（DECT）尿酸（UA）肾血症患病率的研究，探讨原发性痛风患者肾结石的危险因素。八十四个连续痛风患者接受了尿路超声检查或DECT以确认存在肾结石的存在。还采用尿液和血液样本进行实验室分析。四十一体受试者（48.8％）诊断出肾血症病; 38有一个肾结石。 38例患者中三十二例经历了DECT扫描，27名患者在DECT中患有肾脏病。其中，63.0％（17/27）和14.8％（4/21）分别具有纯UA和UA的混合石，22.2％（6/27）具有非UA石。那些患有肾的人患有更频繁的急剧发作，并且痛风的疾病持续时间更长。在81％的患者中发现了至少一种尿生物化学异常。四十四（55.0％）患者呈现了低鼠。四十三（51.8％）患者尿量低。 36名患者中存在过度酸性尿（UAU）（44.4％）。 Heathurocosuria仅在十（12.2％）患者中发现。与非典型群体相比，岩石基团更容易有uau。二元逻辑回归显示，女性性别是一种保护因素，而痛风和低尿pH的疾病持续时间是肾血症病的危险因素。我们的结果表明，肾血症，特别是UA石头，比以前的痛风患者报告更常见，并且痛风的疾病持续时间和低尿液pH值是肾血红病的危险因素。

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