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首页> 外文期刊>BMC Pediatrics >Adverse childhood experiences and the cardiovascular health of children: a cross-sectional study
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Adverse childhood experiences and the cardiovascular health of children: a cross-sectional study

机译：儿童经验和儿童心血管健康：横断面研究

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Background Adverse childhood experiences (ACEs), such as abuse, household dysfunction, and neglect, have been shown to increase adults’ risk of developing chronic conditions and risk factors for chronic conditions, including cardiovascular disease (CVD). Much less work has investigated the effect of ACEs on children’s physical health status that may lead to adult chronic health conditions. Therefore, the present study examined the relationship between ACEs and early childhood risk factors for adult cardiovascular disease. Methods 1 234 grade six to eight students participated in school-based data collection, which included resting measures of blood pressure (BP), heart rate (HR), body mass index (BMI) and waist circumference (WC). Parents of these children completed an inventory of ACEs taken from the Childhood Trust Events Survey. Linear regression models were used to assess the relationship between experiencing more than 4 ACEs experienced, systolic BP, HR, BMI and WC. In additional analysis, ACEs were assessed ordinally in their relationship with systolic BP, HR, and BMI as well as clinical obesity and hypertension status. Results After adjustment for family education, income, age, sex, physical activity, and parental history of hypertension, and WC for HR models, four or more ACEs had a significant effect on HR (b?=?1.8?bpm, 95% CI (0.1-3.6)) BMI (b =1.1?kg/m2, 95% CI (0.5-1.8)), and WC (b?=?3.6?cm, 95% CI (1.8-5.3)). A dose–response relationship between ACE accumulation and both BMI and WC was also found to be significant. Furthermore, accumulation of 4 or more ACEs was significantly associated with clinical obesity (95th percentile), after controlling for the aforementioned covariates. Conclusions In a community sample of grade six to eight children, accumulation of 4 or more ACEs significantly increased BMI, WC and resting HR. Therefore, risk factors related to reported associations between ACEs and cardiovascular outcomes among adults are identifiable in childhood suggesting earlier interventions to reduce CVD risk are required.
机译：背景技术较恶劣的童年经历（ACE），例如滥用，家庭功能障碍和忽视，已被证明增加成年人发育慢性病症的慢性病症和危险因素，包括心血管疾病（CVD）。工作较少调查了ACE对儿童身体健康状况的影响，可能导致成年慢性健康状况。因此，本研究检测了成人心血管疾病的ACE和早期儿童危险因素之间的关系。方法1 234年级六至八名学生参加了基于学校的数据收集，包括静止血压（BP），心率（HR），体重指数（BMI）和腰围（WC）的休息措施。这些儿童的父母完成了童年信托事件调查中的ACE库存。线性回归模型用于评估体验超过4次aces经验，收缩性BP，HR，BMI和WC之间的关系。在额外的分析中，ACES在与收缩性BP，HR和BMI的关系中进行评估，以及临床肥胖和高血压状态。结果调整家庭教育，收入，年龄，性别，身体活动和高血压的父母史，以及HR模型的WC，4种或更多的AC对HR有显着影响（B？=？1.8？BPM，95％CI （0.1-3.6））BMI（B = 1.1？kg / m 2 ，95％ci（0.5-1.8））和wc（b？= 3.6厘米，95％ci（1.8 -5.3）））。也发现ACE累积和BMI和WC之间的剂量 - 响应关系是显着的。此外，在控制上述协变量之后，4或更多AC的积累与临床肥胖（95 Th 百分位数）显着相关。结论在六级至八个儿童的社区样本中，累积4种或更多的AC，BMI，WC和休息的人力资源显着增加。因此，在童年中，童年中，童年的危险因素与成人之间的ACE和心血管成果之间的关联有关的危险因素是必要的，以减少CVD风险的早期干预措施。

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