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首页> 外文期刊>BMC Pediatrics >Timing of liver transplantation for pediatric acute liver failure due to mushroom poisoning: a case report and literature review
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Timing of liver transplantation for pediatric acute liver failure due to mushroom poisoning: a case report and literature review

机译：蘑菇中毒引起的小儿急性肝功能衰竭的肝移植定时 - 案例报告与文献综述

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BACKGROUND:Pediatric acute liver failure is a rare, life-threatening illness. Mushroom poisoning is a rare etiology. For patients with irreversible pediatric acute liver failure, liver transplantation is the ultimate lifesaving therapy. However, it is difficult to determine the optimal timing of transplantation. Here, we present a case of pediatric acute liver failure due to mushroom poisoning in northeastern China. He was treated with liver transplantation and recovered. To our knowledge, there are few reports about liver transplantation for pediatric acute liver failure caused by mushroom poisoning in mainland China.CASE PRESENTATION:The patient was a previously healthy 9-year-old boy who gradually developed nausea, vomiting, jaundice and coma within 5?days after ingesting mushrooms. He was diagnosed with mushroom poisoning and acute liver failure. He was treated with conservative care but still deteriorated. On the 7th day after poisoning, he underwent LT due to grade IV hepatic encephalopathy. Twenty days later, he recovered and was discharged. A review of the literature revealed that the specific criteria and optimal timing of transplantation remain to be determined.CONCLUSIONS:Patients with pediatric acute liver failure should be transferred to a center with a transplant unit early. Once conservative treatment fails, liver transplantation should be performed.
机译：背景：小儿急性肝功能衰竭是一种罕见的危及生命的疾病。蘑菇中毒是一种罕见的病因。对于患有不可逆转的小儿急性肝衰竭的患者，肝移植是最终的救生疗法。然而，难以确定移植的最佳时间。在这里，我们出示了中国东北部蘑菇中毒因子儿科急性肝衰竭的情况。他被肝移植治疗并恢复。据我们所知，肝脏移植对中国大陆中毒引起的小儿急性肝衰竭的报道很少。Case演示：患者是一个以前健康的9岁男孩，逐渐发育恶心，呕吐，黄疸和昏迷5？摄入蘑菇后的天。他被诊断出患有蘑菇中毒和急性肝衰竭。他被保守护理治疗，但仍然恶化。在中毒后的第7天，他完成了IV级肝脑病的LT。二十天后，他恢复并被解雇了。对文献的综述显示，移植的具体标准仍然确定。结论：儿科急性肝功能衰竭的患者应尽早与移植单元转移到中心。一旦保守治疗失败，应进行肝移植。

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