...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Psychiatry >Treatment of chronically depressed patients: A multisite randomized controlled trial testing the effectiveness of 'Cognitive Behavioral Analysis System of Psychotherapy' (CBASP) for chronic depressions versus usual secondary care
【24h】

Treatment of chronically depressed patients: A multisite randomized controlled trial testing the effectiveness of 'Cognitive Behavioral Analysis System of Psychotherapy' (CBASP) for chronic depressions versus usual secondary care

机译：治疗慢性抑制患者：多路随机对照试验检测慢性萧条的心理治疗（CBASP）对慢性萧条的有效性与常用次要护理

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background 'Cognitive Behavioral Analysis System of Psychotherapy' (CBASP) is a form of psychotherapy specifically developed for patients with chronic depression. In a study in the U.S., remarkable favorable effects of CBASP have been demonstrated. However, no other studies have as yet replicated these findings and CBASP has not been tested outside the United States. This protocol describes a randomized controlled trial on the effectiveness of CBASP in the Netherlands. Methods/Design The purpose of the present paper is to report the study protocol of a multisite randomized controlled trial testing the effectiveness of 'Cognitive Behavioral Analysis System of Psychotherapy' (CBASP) for chronic depression in the Netherlands. In this study, CBASP in combination with medication, will be tested versus usual secondary care in combination with medication. The aim is to recruit 160 patients from three mental health care organizations. Depressive symptoms will be assessed at baseline, after 8 weeks, 16 weeks, 32 weeks and 52 weeks, using the 28-item Inventory for Depressive Symptomatology (IDS). Effect modification by co morbid anxiety, alcohol consumption, general and social functioning and working alliance will be tested. GEE analyses of covariance, controlling for baseline value and center will be used to estimate the overall treatment effectiveness (difference in IDS score) at post-treatment and follow up. The primary analysis will be by 'intention to treat' using double sided tests. An economic analysis will compare the two groups in terms of mean costs and cost-effectiveness from a societal perspective. Discussion The study will provide an answer to the question whether the favorable effects of CBASP can be replicated outside the US. Trial Registration The Dutch Cochrane Center, NTR1090.
机译：背景“心理疗法的认知行为分析系统”（CBASP）是针对慢性抑郁症患者专门开发的心理治疗的形式。在美国的一项研究中，已经证明了CBASP的显着良好影响。然而，没有其他研究已经复制了这些发现，而CBASP尚未在美国以外进行测试。本协议描述了对荷兰CBASP的有效性的随机对照试验。方法/设计本文的目的是报告多立体随机对照试验的研究方案，测试荷兰慢性抑郁症的“心理疗法”（CBASP）的有效性。在本研究中，CBASP与药物组合，将与用药组合测试。目的是从三种心理保健组织招募160名患者。使用28项库存的抑郁症状（IDS），将在8周，16周，32周和52周内评估抑郁症状。通过CO病态焦虑，饮酒，一般和社会运作和工作联盟进行效果修饰。协方差的GEE分析，控制基线价值和中心的控制将用于估算后处理和跟进的整体治疗效果（IDS评分差异）。主要分析将使用双面测试“意图治疗”。经济学分析将在社会角度与平均成本和成本效益方面进行比较两组。讨论该研究将对问题的问题提供答案，无论CBASP是否可以在美国以外复制。试验登记荷兰Cochrane中心，NTR1090。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号