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首页> 外文期刊>Cancer Management and Research >Diagnosis and Surgical Treatment and Pathological Findings of Solid Pseudopapillary Tumor of the Pancreas: A Single-Institution Experience
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Diagnosis and Surgical Treatment and Pathological Findings of Solid Pseudopapillary Tumor of the Pancreas: A Single-Institution Experience

机译：胰腺固体伪肿瘤的诊断和外科治疗和病理发现：单机制经验

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Purpose: To investigate the diagnosis, surgical treatment, and pathology of solid pseudopapillary tumors of the pancreas in our institution. Patients and Methods: We retrospectively analyzed the demographic details, clinical features, imaging findings, and pathological findings of 87 patients with a confirmed diagnosis of solid pseudopapillary tumors of the pancreas (SPTP) and underwent surgery in Tongji Hospital of Tongji Medical College, over a period of 8 years from 2011 to 2018. Results: Our study involved a total of 87 patients (16 males and 71 females) with a mean age of 31.3± 13.1 years (range: 10– 61 years). The main compliant was abdominal pain or discomfort (n=49) and the median tumor size was 58.6± 31.7 mm (range: 16– 156mm). Tumors were located in the head (27 patients, 31%), the neck (13 patients, 15%), and the body and tail (47 patients, 54%). There were no significant differences between the patients in terms of sex, age, or tumor location. Partial pancreatectomy was performed in 79 patients, enucleation in six patients, and total pancreatectomy in two patients. R0 resection was achieved in 86 patients. The postoperative morbidity was 36.8%, and the main complication was pancreatic fistula. Pathological examination and immunohistochemical markers were used to provide a final diagnosis. The main follow-up period was 46 months (range: 13– 97 months). At the end of the follow-up period, 86 patients were alive and had not experienced recurrence; one patient was lost to follow-up. Conclusion: The accurate diagnosis of SPTP is vital. Our data showed that surgical resection is safe and associated with low morbidity and mortality rates. Pathological findings can play an important role in diagnosis and long-term survival.
机译：目的：探讨我所在机构胰腺固体伪肿瘤的诊断，手术治疗和病理学。患者和方法：我们回顾性分析了87名患者的人口统计学细节，临床特征，成像结果和病理发现，确诊诊断胰腺（SPTP）的固体伪肿瘤和同济医学院同济医院的手术，AD结果从2011年到2018年的8年。结果：我们的研究涉及共有87名患者（16名男性和71名女性），平均年龄为31.3±13.1岁（范围：10-61岁）。主要符合副作用是腹痛或不适（n = 49），中值肿瘤尺寸为58.6±31.7 mm（范围：16-156mm）。肿瘤位于头部（27名患者，31％），颈部（13名患者，15％）和身体和尾部（47名患者，54％）。患者在性别，年龄或肿瘤位置之间没有显着差异。部分胰乳酶切除术在79名患者中进行，六名患者中的脑内，以及两名患者的总胰乳酶切除术。在86名患者中取得了R0切除术。术后发病率为36.8％，主要并发症是胰腺瘘。使用病理检查和免疫组织化学标志物来提供最终的诊断。主要随访期为46个月（范围：13-97个月）。在随访期结束时，86名患者还活着，并没有经历过复发;一名患者失去了随访。结论：SPTP的准确诊断至关重要。我们的数据显示，手术切除是安全的，与发病率和死亡率低相关。病理发现可以在诊断和长期存活中发挥重要作用。

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