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Suboptimal inhaler medication adherence and incorrect technique are common among chronic obstructive pulmonary disease patients

机译:次优吸入药物依从性和不正确的技术在慢性阻塞性肺病患者中常见

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Patients with chronic obstructive pulmonary disease (COPD) are routinely prescribed one or more inhaled medications. Adherence to inhaler medications and correct inhaler device technique are crucial to successful COPD management. The goals of this study were to estimate adherence and inhaler technique in a cohort of COPD patients. This was an observational study conducted on a sample of 150 COPD patients. Medication adherence was assessed using the Medication Adherence Report Scale (MARS). Inhaler technique was assessed using standardized checklists. Clinical data were collected using a proforma. Of the 150 patients (mean age 70.3 years, 52% male), 58% reported suboptimal adherence (MARS ≤ 24). High adherence to therapy (MARS = 25) was associated with older age (p = 0.001), but not any of the other studied variables. Medication non-adherence was not associated with COPD exacerbations. Errors (≥ 1) in inhaler technique were common across all of the types of inhaler devices reportedly used by patients, with the highest proportion of errors among Turbuhaler users (83%) and the least proportion of errors among Handihaler users (50%). No clinical variables were associated with errors in inhaler technique. Suboptimal adherence and errors in inhaler technique are common among COPD patients. No clinical variables to assist in the prediction of medication non-adherence and poor inhaler technique were identifiable. Consequently, regular assessment of medication adherence and inhaler technique should be incorporated into routine clinical practice to facilitate improved health outcomes among patients with COPD.
机译:慢性阻塞性肺病(COPD)的患者常规规定了一种或多种吸入药物。坚持吸入药物和正确吸入器装置技术对于成功的COPD管理至关重要。本研究的目标是估算COPD患者队列中的依从性和吸入器技术。这是对150名COPD患者的样本进行的观察研究。使用药物申请报告规模(MARS)评估药物依从性。使用标准化的清单评估吸入器技术。使用形式收集临床数据。 150名患者(平均年龄为70.3岁,男性52%),报告的次优粘附(MARS≤24)。对治疗的高粘附(Mars = 25)与年龄较大(P = 0.001)相关,但不是其他其他研究的变量。药物非粘附与COPD加剧无关。吸入器技术中的错误(≥1)在何种类型的患者使用的所有类型的吸入器设备中都是常见的,并且涡轮母用户(83%)中的最高误差比例最高,并且手机用户中最少的错误比例最低(50%)。没有临床变量与吸入器技术的误差相关。吸入器技术的次优依从性和错误在COPD患者中是常见的。没有临床变量来协助预测药物非粘附和较差的吸入技术是可识别的。因此,应定期评估药物粘附和吸入器技术,应纳入常规的临床实践,以促进COPD患者的改善健康结果。

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