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首页> 外文期刊>Circulation journal >Characteristics of Induced Ventricular Fibrillation Cycle Length in Symptomatic Brugada Syndrome Patients
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Characteristics of Induced Ventricular Fibrillation Cycle Length in Symptomatic Brugada Syndrome Patients

机译：症状巴鲁达综合征患者诱导心室纤维化循环长度的特征

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Background: Limited information is available on the ventricular fibrillation (VF) spectrum in Brugada syndrome (BS) patients. We clarified differences in the VF cycle length (CL) using fast-Fourier transformation (FFT) analysis in symptomatic and asymptomatic BS patients. Methods and Results: VF was induced by pacing from the right ventricular (RV) apex and/or RV outflow tract (RVOT) for >8s. A 4096-point FFT analysis of results from 28 male BS patients (51.1±13.7 years old) was performed. Dominant frequency (DF) from phases 1 (4s) to 6 was obtained at 2-s intervals. The average DF from surface and intracardiac electrograms (ECG: DFECG; ICE: DFICE,, respectively) was compared between symptomatic and asymptomatic patients. Symptomatic patients had a significantly shorter effective refractory period at a CL of 600ms at the RVOT than asymptomatic patients. DFECG significantly increased with phase (5.64±0.32Hz in phase 1 to 6.16±0.52Hz in phase 6) and was significantly higher in symptomatic patients than in asymptomatic patients. DFICE had the same characteristics as DFECG. Conclusions: Induced VF in BS patients can be characterized using FFT analysis. Our data support the hypothesis that symptomatic patients have a significantly shorter VF CL than asymptomatic patients. ( Circ J 2012; 76: 624-633)
机译：背景：有限的信息可在Brugada综合征（BS）患者的心室纤维化（VF）谱上获得。我们在症状和无症状BS患者中使用快速傅里叶变换（FFT）分析阐明了VF循环长度（CL）的差异。方法和结果：VF通过从右心室（RV）顶点和/或RV流出道（RVOT）的起搏诱导> 8S。对28名男性BS患者（51.1±13.7岁）的结果进行了4096点FFT分析。从两相1（4S）至6的主导频率（DF）以2-S间隔获得。从表面和心内电视图的平均DF（ECG：DF ECG ;冰：分别在症状和无症状患者之间进行冰：DF 冰，。症状患者在RVOT在600ms的CL处具有明显较短的有效耐火剂，而不是无症状患者。 DF ECG 在相6分钟内显着增加（5.64±0.32Hz，6.16阶段6.16±0.52Hz），症状患者显着高于无症状患者。 DF Ice 具有与DF ECG 相同的特征。结论：使用FFT分析，诱导BS患者的VF。我们的数据支持假设症状患者比无症状患者具有明显较短的VF CL。 （九2012年CIRC; 76：624-633）

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