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首页> 外文期刊>Circulation journal >New Strategy for Detection of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Based on Cardiac Multi-Detector Computed Tomography and Treadmill Test
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New Strategy for Detection of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Based on Cardiac Multi-Detector Computed Tomography and Treadmill Test

机译：基于心脏多探测器的2型糖尿病患者患者亚临床冠状动脉粥样硬化的新策略计算断层扫描和跑步机试验

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Background: ?The current screening strategy for subclinical coronary atherosclerosis in asymptomatic diabetic patients is not sufficient in real clinical practice. A new strategy was investigated that uses cardiac multi-detector computed tomography (MDCT) and a treadmill test (TMT). Methods and Results: ?A total of 445 self-referred asymptomatic diabetic patients underwent cardiac MDCT. The treatment plan was determined according to the new strategy that uses MDCT and TMT. All patients underwent clinical follow-up and cardiac events were investigated. The incidence of subclinical atherosclerosis was 49.4%. The group without plaque underwent clinical follow-up without treatment and did not experience any cardiac events in 675.1 person-years of follow-up. Among patients with subclinical atherosclerosis without significant stenosis (n=136) who received medical treatment only, 11 patients experienced cardiac events over 326.4 person-years. The patients with significant stenosis (n=84) underwent TMT. Patients with positive TMT (n=14) underwent coronary angiograms and revascularization therapy was performed in all of them over 39.2 person-years. Patients with negative TMT (n=70) underwent medical treatment, and 27 of them experienced cardiac events. The incidence of cardiac death was 0% during 3 years of follow-up. Conclusions: ?The new strategy for detecting subclinical atherosclerosis on MDCT combined with TMT may be a useful method for minimizing the mortality rate from cardiovascular disease in asymptomatic diabetic patients.??( Circ J ?2014; 78: 671–678)
机译：背景：无症状糖尿病患者的亚临床冠状动脉粥样硬化的当前筛选策略在真正的临床实践中不足。研究了一种使用心脏多探测器计算机断层扫描（MDCT）和跑步机测试（TMT）的新策略。方法和结果：共有445例自我引用的无症状糖尿病患者接受了心脏MDCT。治疗计划是根据使用MDCT和TMT的新策略确定。研究了所有患者接受了临床随访和心脏事件。亚临床动脉粥样硬化的发生率为49.4％。该小组没有斑块接受临床随访而没有治疗，并没有在675.1人的后续行动中经历任何心脏事件。在没有明显狭窄的患者患者中，没有显着狭窄（n = 136），仅接受医疗治疗，11名患者经历了326.4人的心脏事件。具有显着狭窄（n = 84）的患者接受了TMT。患有阳性TMT（n = 14）的患者在所有39.2人的所有人中都进行了冠状动脉血管造影和血运重建治疗。阴性TMT（n = 70）的患者接受医疗治疗，其中27名经历了心脏事件。 3年后心脏死亡的发生率为0％。结论：检测亚临床动脉粥样硬化的新策略与TMT相结合，可以是最小化无症状糖尿病患者心血管疾病中死亡率的有用方法。??（电池J？2014; 78：671-678）

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