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Placenta Accreta in a Woman with Childhood Uterine Irradiation: A Case Report and Literature Review

机译:胎盘Accreta在一个有儿童子宫辐照的女人中:案例报告和文献综述

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The pregnancies of childhood cancer survivors who have received uterine irradiation are associated with a high risk of several obstetrical complications, including placenta accreta. The present case was a 26-year-old pregnant woman with a history of myelodysplastic syndrome treated with umbilical cord blood transplantation following chemotherapy and total body irradiation at the age of 10. Despite every possible measure to prevent preterm labor, uterine contractions became uncontrollable and a female infant weighing 892?g was vaginally delivered at 27+4 weeks of gestation. Under the postpartum ultrasonographic diagnosis of placenta accreta, we selected to leave the placenta in situ. Although emergency bilateral uterine artery embolization was required, complete resorption of the residual placenta was accomplished on the 115th day postpartum. Our experience highlighted the following points. (1) The expectant management of placenta accreta arising in an irradiated uterus may not only fulfill fertility preservation, but may also reduce possible risks associated with cesarean hysterectomy. (2) Due to extreme thinning of and a poor blood supply to the myometrium, reaching an antepartum diagnosis of placenta accreta in an irradiated uterus is difficult. (3) The recurrence of placenta accreta in subsequent pregnancies needs to be considered after successful preservation of the uterus.
机译:接受子宫辐照的儿童癌症幸存者的怀孕与胎盘患者有几种产科并发症的高风险有关。本案例是一名26岁的孕妇,患有脐血移植治疗的髓细胞增强综合症史,在化疗后和10岁时的全身照射。尽管每种可能的措施都可以防止早产劳动,子宫收缩变得无法控制重量为892次的女性婴儿在妊娠的27 + 4周内含糊地递送。在产后超声诊断的胎盘癌症下,我们选择原地离开胎盘。虽然需要紧急双侧子宫动脉栓塞,但在产后的115天完成了残留胎盘的完全吸收。我们的经验强调了以下几点。 (1)辐照子宫内引起的胎盘血质雷塔的预期管理可能不仅可能达到生育能力,而且还可以减少与剖宫产功能相关的可能性。 (2)由于对肌肉病毒的极端稀疏和血液供应不良,达到辐照子宫中胎盘诊断的胎儿诊断是困难的。 (3)在成功保存子宫后,需要考虑胎盘Accreta的复发。

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