• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Acute and critical care. >Suggestions and tips regarding polymyxin B-immobilized fiber column direct hemoperfusion of neonates with sepsis
【24h】

Suggestions and tips regarding polymyxin B-immobilized fiber column direct hemoperfusion of neonates with sepsis

机译：关于多辛B-固定化纤维柱直接血液灌注脓毒症的建议和提示

获取原文
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

I read with great interest the case report entitled, “A successful application of adult polymyxinB-immobilized fiber column hemoperfusion to a neonate with septic shock” by Kim et al [1].In this case, a female neonate was born at a gestational age of 38 weeks with a birth weight of3.0 kg. She developed late-onset septic shock caused by a carbapenem-resistant Acinetobacterbaumannii infection and was treated with extracorporeal membrane oxygenation (ECMO)and adult polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP). Theseinterventions yielded significant short-term improvements in cardiopulmonary function.However, the patient died of multiorgan dysfunction syndrome two days after discontinuationof ECMO and PMX-DHP. The authors concluded that PMX-DHP could be used as anadjunctive treatment for selected neonates with Gram-negative bacterial septic shock. AlthoughI partly agree with the authors, my colleagues and I recently reported that the effectivenessof PMX-DHP was limited in neonates with septic shock due to late-onset sepsis (onset 72 hours after birth) [2]. I wish to comment on the use of PMX-DHP for neonatal septicshock and provide suggestions based on our experiences.
机译：我非常感兴趣地题为Kim等人的案例报告，“成功地将成人聚吡嗪 - 固定的纤维柱血液灌注到脓毒休克的新生儿”[1]。在这种情况下，一个女性新生儿出生在胎龄38周，出生体重3.0千克。她开发了由Carbapenem抗性抗癌杆菌感染引起的晚期脓毒性冲击，并用体外膜氧合（ECMO）和成人多羟嗪B-固定化纤维柱直接血液灌注（PMX-DHP）。这些Interventions在心肺功能中产生了显着的短期改善。然而，患者在Ecmo和PMX-DHP中停止后两天死于多功能功能障碍综合征。作者得出结论，PMX-DHP可用作具有革兰氏阴性细菌抑制休克的选择的新生儿的抗植物治疗。尽管我一道与作者，我的同事和我最近报道，由于晚期败血症（出生后72小时发作），PMX-DHP的有效性受到脓毒症的新生儿的限制[2] [2]。我希望评论使用PMX-DHP的新生儿效果，并根据我们的经验提供建议。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号