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Alcohol Consumption Is Associated with Hypogonadism and Decreased Sexual Function in Ghanaian Diabetics

机译:酒精消费与未性腺减少症有关,在加纳糖尿病患者中减少性功能

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Introduction: Alcohol usage has largely been seen as a risk factor for the development of sexual dysfunction as well as erectile dysfunction. Others have reported that prolonged alcohol usage and abuse is compatible with normal sexual function in the absence of endocrinological problems as well as hepatic dysfunction. About seventy five (75) percent of alcoholics have various sexual difficulties with improvements in sexual functions occurring after treatment of alcoholism and psychosexual therapy. It is evident from the various reports over the years that mild and occasional alcohol usage is not as much implicated in the causation of SD and its other forms as heavy, addictive or dependent alcohol usage. Alcohol usage has also long been linked to hypogonadism, testicular atrophy as well as leydig cell toxicity. Alcohol induced hypogonadism has been reported to resolve after withdrawal of alcohol use. Since both diabetes and alcohol usage have been strongly associated with both hypogonadism and sexual dysfunction, it is logical to expect that diabetics who frequently consume alcohol will have a worsened hypogonadal state and sexual function. This research therefore seeks to provide evidence of an association between alcohol consumption in diabetics and a worsened sexual dysfunction in comparison to diabetics who did not consume alcohol. Methods: Type II diabetic patients attending the Diabetic Clinic at the Maamobi General Hospital between the periods of January 2010 and March 2011 were consecutively recruited for this study. Diabetics with other known endocrinological diseases and physical disabilities were excluded from the study. Sexual function was assessed using the GRISS-M. Early morning fasting samples were used in lipid and testosterone profile assays. Results: Study participants who consumed alcohol recorded higher levels of triglycerides and LDL-Cholesterol. They also recorded significantly lower levels of bioavailable testosterone. Furthermore they also recorded higher scores for impotence, premature ejaculation, non-sensuality and infrequency but lower scores for avoidance and were about six times more likely to be infrequent in their sexual activity in comparison with those who did not consume alcohol. Conclusion: Alcohol consumption among diabetic males is associated with hypogonadism and has an impact on several domains of male sexual function. Diabetic males should be advised to avoid alcohol abuse in order to facilitate the management of diabetes associated sexual dysfunction.
机译:简介:酒精使用主要被视为性功能障碍和勃起功能障碍的危险因素。其他人报告称,在没有内分泌问题以及肝功能障碍的情况下,延长的酒精使用和滥用与正常的性功能相容。大约75(75)%的酗酒者在治疗酒精中毒和心理治疗后发生了各种性困难,改善了性功能。从多年来的各种报告中显而易见的是,温和和偶尔的酒精用法并不像SD的因果关系那么多,其它形式是重,上瘾或依赖的酒精使用。酒精使用量也很长一直与过毒动动物,睾丸萎缩以及Leydig细胞毒性相连。据报道,酒精诱导的性腺病毒在戒断酒精使用后解决。由于糖尿病和酒精使用都与性交失调和性功能障碍都强烈关联,因此期望经常消耗酒精的糖尿病患者具有恶化的低因素状态和性功能。因此,该研究旨在提供糖尿病患者饮酒和不消耗酒精的糖尿病患者的性功能障碍之间的饮酒之间关联的证据。方法:II型糖尿病患者,在2010年1月和2011年3月间的Maamobi综合医院参加了糖尿病诊所的糖尿病患者是为了招募这项研究。糖尿病患者与其他已知的内分泌疾病和身体残疾被排除在研究之外。使用Griss-M评估性功能。清晨禁食样品用于脂质和睾酮型材分析。结果:研究饮酒的参与者记录了更高水平的甘油三酯和LDL-胆固醇。它们还记录了较低的生物可利用睾酮水平。此外,他们还记录了阳痿,早泄,非感性,不敏感性,但避免得分的得分更高,与没有消费酒精的人相比,在其性活动中罕见的可能性少六倍。结论:糖尿病雄性中的酒精消耗与低因作用相关,对男性性功能的几个域产生影响。应建议糖尿病雄性以避免酒精滥用,以促进糖尿病的管理相关性功能障碍。

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