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首页> 外文期刊>Advances in Surgical Sciences >Visual Status of HIV and Non-HIV Infected Children in Relation to Anti-retroviral Drug Use and CD4+ Count in Jos, Plateau State Nigeria
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Visual Status of HIV and Non-HIV Infected Children in Relation to Anti-retroviral Drug Use and CD4+ Count in Jos, Plateau State Nigeria

机译：艾滋病毒和非HIV感染儿童的视觉状况与抗逆转录病毒药物使用和JOS，高原州尼日利亚的CD4 +计数

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In immunodeficiency diseases such as Human Immunodeficiency Virus (HIV) infection, various body functions may be affected; visual function could be one of them. In a child, there are predictable adverse outcomes of the disease that bother physical and mental development. This study sought to investigate any potential compromise of visual function amongst HIV-infected children on anti-retroviral drugs known as Highly Active Antiretroviral Therapy (HAART) use by comparing the visual acuity, colour sense and field of vision in infected and non-infected children. One hundred (100) children aged between 5 to 15 years consisting of fifty (50) HIV infected and fifty (50) non-HIV infected were selected through random sampling. Visual acuity test (Snellen's method), colour sense test (Ishihara chart method) and field of vision test (confrontational method) were carried out. Latest Cluster of Differentiation 4 (CD4+) count of the HIV infected subjects also was collected. Statistical analysis was carried out using the Student T Test and ANOVA. The mean visual acuity of Human Immunodeficiency Virus (HIV) infected children was slightly low compared to the negative group (94.24.61and 96.412.58 respectively) but was not statistically significant (p0.05). The mean of Ishihara colour sense test and that of the field of vision test also showed no statistically significant change between infected and non-infected children. Mean CD4+ count of the HIV infected children increased with age and use of anti-retroviral drugs. From 11 to 15 years, percentage defect in visual acuity increased amongst the HIV infected children, compared to the other ages but not statistically significant (p0.05). It was concluded that visual acuity decreases slightly with improving CD4+ count and increasing age, for HIV positive children on anti-retroviral drugs. These parameters could be observed in subsequent years and subjects monitored for further investigation.
机译：在免疫缺陷疾病如人免疫缺陷病毒（HIV）感染，各种身体功能可能受到影响;可视化功能可能是其中之一。在一个孩子，疾病的可预测不良结果是扰乱身心发展的疾病。本研究试图通过比较感染和未感染的儿童的视力（HAART）使用的抗逆转录病毒药物对抗逆转录病毒药物的抗逆转录病毒药物中的艾滋病毒感染儿童中的任何潜在折衷。 。通过随机抽样选出5至15年的5至15年的儿童，其中50（50）艾滋病毒感染和五十（50）个非HIV感染。进行视力测试（Snellen的方法），进行颜色读取测试（ISHIHARA图表方法）和视野测试（对抗方法）。收集了最新的分化4（CD4 +）计数的HIV感染受试者的计数。使用学生T测试和ANOVA进行统计分析。与阴性组相比，人类免疫缺陷病毒（HIV）感染儿童的平均视力略微低（分别为94.24.61和96.412.58，但没有统计学意义（P> 0.05）。 Ishihara颜色感测试验的平均值以及视野测试领域也显示出感染和未感染的儿童之间没有统计学显着的变化。平均CD4 +计数HIV感染的儿童随着年龄和使用抗逆转录病毒药物而增加。从11〜15年来，与其他年龄相比但没有统计学意义（P> 0.05），艾滋病病毒感染儿童的缺陷百分比增加结论是，随着抗逆转录病毒药物的艾滋病毒阳性儿童，视力随着改善CD4 +计数和增加的年龄而略有降低。在随后的几年和监测科目进行进一步调查的主题中可以观察到这些参数。

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