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首页> 外文期刊>African Journal of Biotechnology >Antibacterial, antioxidant and cytotoxic activities of extracts from the thermophilic green alga, Cosmarium sp.
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Antibacterial, antioxidant and cytotoxic activities of extracts from the thermophilic green alga, Cosmarium sp.

机译：来自嗜热绿地藻类，Cosmarium sp的抗菌，抗氧化和细胞毒性活性。

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摘要

Unicellular green algal strains, identified as?Cosmarium?(Chlorophyta), were isolated from A?n-Echeffa hot spring in north Tunisia. Different extracts (methanol, hexane, acetone, acetone: methanol and water) obtained from both biomass and extracellular polysaccharides (EPS) were evaluated for their antibacterial, antioxidant and cytotoxic activities. First, extracts were tested?in vitro?for eventual antibacterial activities against a collection of Gram positive and negative bacteria. Most extracts (biomass and EPS) showed significant antibacterial effects, with minimum inhibitory concentrations (MIC) ranging from 28 to 85 μg/ml for biomass and 50 to 150 μg/ml for EPS. Moreover, based on the capacity of each sample to scavenge the ABTS radical cation, we revealed that the EPS aqueous extract presented a moderate antioxidant activity (24.97%). Finally, the toxicity of the biomass extracts was evaluated using the brine shrimp?Artemia salina, as test organism. All extracts were identified as non-toxic (LC50?> 400 μg/ml).
机译：单细胞绿藻菌株，被鉴定为cosmarium？（叶绿素），从北突尼斯北突尼斯的N-Echeffa温泉中分离出来。评价由生物质和细胞外多糖（EPS）获得的不同提取物（甲醇，己烷，丙酮，丙酮：甲醇和水），用于其抗菌，抗氧化和细胞毒性活性。首先，测试萃取物？体外？用于针对革兰氏阳性和阴性细菌的集合的最终抗菌活性。大多数提取物（生物量和EPS）显示出显着的抗菌作用，最小抑制浓度（MIC）为28至85μg/ ml，用于EPS的50至150μg/ ml。此外，基于每种样品的容量清除ABTS激进阳离子，我们透露了EPS水提取物呈现了中度抗氧化活性（24.97％）。最后，使用盐水虾（Astemia Salina）评估生物质提取物的毒性，作为测试生物。将所有提取物鉴定为无毒（LC50→400μg/ ml）。

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