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首页> 外文期刊>African Journal of Cellular Pathology >SEMEN CHARACTERISTICS OF WISTAR RATS TREATED WITH METHANOLIC EXTRACT OF JATROPHA GOSSYPIFOLIA
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SEMEN CHARACTERISTICS OF WISTAR RATS TREATED WITH METHANOLIC EXTRACT OF JATROPHA GOSSYPIFOLIA

机译：用甲醇溶酶甲基吡糊精治疗Wistar大鼠的精液特征

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Aim: The study was designed to determine the effect of methanolic leave extract of Jatropha gossypifolia on semen characteristics in Wistar rats.Methods: Twenty-five male Wistar rats were divided into 5 groups (A, B, C, D and E) comprising 5 rats each. Rats in group A served as control, and were administered distilled water per os for 21 days, while rats in groups B, C, D and E were administered oral 100, 300, 500 and 1000 mg/kg bodyweight of Jatropha gossypifolia leaf extract for 21 days, respectively. At the end of the treatment period, the rats were humanly sacrificed and semen was collected by open castration and evaluated.Results: There was a dose dependent decrease in the mass activity, sperm motility, sperm concentration and percentage live sperm cells of the treated groups. These were significantly (p<0.05) different from the control group except group B. Percentage abnormalities characterized by detached head, double head, curved head, giant head, coiled tail, curved tail and curved mid-piece were seen during the study. These abnormalities were significantly (p<0.05) higher in the treated groups (C – E) than the control.Conclusion: It was concluded from the study that Jatropha gossypifolia leave extract above 100 mg/kg is capable of disrupting the reproductive process of male Wistar rats through poor semen characteristics. However, extract at not more than100 mg/kg body weight may be safe.
机译：目的旨在确定Jatropha Gossypifolia对Wistar大鼠精液特性的甲烷醇留下提取物的影响。方法：将二十五只雄性Wistar大鼠分成5组（A，B，C，D和E）5老鼠每个大鼠。 A组中的大鼠作为对照，每个OS给予蒸馏水21天，而B组，C，D和E基团的大鼠施用口服100,300,500和1000 mg / kg体重的麻风树状糖尿病叶提取物分别为21天。在治疗期结束时，大鼠被人类处死，通过开放阉割和评估收集精液。结果：肿块活性，精子运动，精子浓度和治疗组的活体细胞百分比的剂量依赖性降低。除了群B组，这些显着（p <0.05）不同于对照组。在研究期间，在研究期间看到了独立的头部，双头，弯曲头，巨头，卷尾，弯曲的尾巴，弯曲尾巴和弯曲的中间件的百分比异常。治疗组（C-E）中的这些异常显着（p <0.05）比对照组更高（p <0.05）。结论：从100mg / kg高于100 mg / kg的Jatropha Gossypifolia留言提取物中讲述了雄性Wistar大鼠通过差的精液特征。然而，提取物不超过100mg / kg体重可能是安全的。

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