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首页> 外文期刊>American Journal of Analytical Chemistry >HPTLC Phytochemical Screening and Hydrophilic Antioxidant Activities of &i&Apium graveolens&/i& L., &i&Cleome gynandra&/i& L., and &i&Hibiscus sabdariffa&/i& L. Used for Diabetes Management
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HPTLC Phytochemical Screening and Hydrophilic Antioxidant Activities of &i&Apium graveolens&/i& L., &i&Cleome gynandra&/i& L., and &i&Hibiscus sabdariffa&/i& L. Used for Diabetes Management

机译：HPTLC植物化学筛选和亲水性抗氧化活性＆ I＆ apium graveolens＆ / i＆ L.，＆ i＆克里姆蒙甘蓝型。 L.，和＆ i＆ Hibiscus sabdariffa＆ / i＆ L.用于糖尿病管理

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Diabetes mellitus is a socially significant disease characterized by chronic hyperglycemia and metabolic disorders of proteins, carbohydrates, and lipids due to reduced function of insulin. Medicinal plants, rich in bioactive components that promote prevention and treatment, are inexpensive and no side effects. Apium graveolens , Cleome gynandra , and Hibiscus sabdariffa from Burkina Faso were investigated for their phytochemical profile and antioxidant activities. The high-performance thin-layer chromatography profile revealed flavonoids, tannins, and sterols in these herbaceous. The Hibiscus sabdariffa methanolic extract exhibited the highest total phenolic (138.4 ± 0.5 mg GAE/g DW) and flavonoid (52.8 ± 0.6 mg RuE/g DW) contents comparatively to Cleome gynandra and Apium graveolens . Hibiscus sabdariffa methanolic extract also presented the highest antioxidant activity (IC_(50) = 0.31 ± 0.002 mg/mL) using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity assay. A high correlation between flavonoid contents and hydrophilic antioxidant activities (r = 0.99) was observed, indicating that flavonoids contribute significatively to these herbaceous antioxidant properties. Apium graveolens , Cleome gynandra, and Hibiscus sabdariffa constitute a natural source of phenolic compounds that could be exploited in diabetes mellitus management.
机译：糖尿病是一种社会显着的疾病，其特征在于由于胰岛素的函数减少，蛋白质，碳水化合物和脂质的代谢紊乱，其特征在于慢性高血糖和脂质的代谢障碍。药用植物，丰富的生物活性组件，促进预防和治疗，是廉价且无副作用。 Apium graveolens，来自Burkina Faso的克里姆摩尔·古曼德拉，以及来自Burkina Faso的Hibiscus Sabdariffa进行了调查的植物化学型材和抗氧化活动。高性能薄层色谱型材揭示了这些草本植物中的黄酮类化合物，单宁和甾醇。 芙蓉Sabdariffa甲烷醇提取物在最高总酚（138.4±0.5mg）和黄酮（52.8±0.6mg rue / g dw）的含量相对较小，相对较小，克里姆姆·古andra和 apium graveolens。 芙蓉Sabdariffa甲烷提取物也使用2,2-二苯基-1-富铬酰基（DPPH）自由基清除能力测定呈现最高的抗氧化活性（IC_（50）= 0.31±0.31±0.31±0.31.002mg / ml）。观察黄酮含量和亲水性抗氧化活性（r = 0.99）之间的高相关，表明黄酮类化合物对这些草本抗氧化剂的性能有影响。 apium graveolens，克里姆蒙犬，和芙蓉萨比德拉构成了酚类化合物的天然来源，可在糖尿病管理中被利用。

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