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Advances in the surgical treatment of esophageal cancer since 1965

机译:1965年以来食管癌手术治疗的进展

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In Japan, the treatment of esophageal cancer has undergone significant development since the Japanese Society for Esophageal Diseases was established in 1965 by Doctors Komei Nakayama, Shigetsugu Katsura, and Ichiro Akakura. When the Society was established, surgery was the first‐line treatment for esophageal cancer. Since then, the Society has been led by three successive chairpersons—Doctors Katsura, Nakayama, and Satoh. Over this time, surgery‐related mortalities declined to 5%‐6% because of the rapid improvements in surgical technique. Beginning in 1980, the bilateral cervical lymph node dissection technique gained attention, and favorable long‐term outcomes were gradually reported. A nationwide questionnaire survey, conducted by the Society in 1990, showed that more favorable long‐term outcomes were achieved by following the three‐field lymph node dissection technique than by following the two‐field lymph node dissection technique. Since then, the three‐field lymph node dissection technique has been recognized and widely used as the standard surgical procedure for treating esophageal cancer. After clinical studies examined the utility of various pre‐ and postoperative adjunctive therapies in outcome improvements, preoperative chemotherapy was recognized as the standard treatment in the therapy guidelines. Additionally, less invasive surgical methods have been developed, including endoscopic and robot‐assisted surgeries, which are applied in general practice now. However, unresectable and recurrent esophageal cancers remain difficult to treat, and additional treatments should be developed.
机译:在日本,自1965年由医生Komei Nakayama,Shigetsugu Katsura和iChiro Akakura建立,自1965年,在日本食管疾病社会成立以来,食管癌的治疗经历了显着发展。当社会建立时,手术是食管癌的一线治疗。从那时起,社会由三个连续的主席 - 医生Katsura,Nakayama和Satoh领导。在此时间上,由于手术技术的快速改善,外科有关的死亡率下降至5%-6%。从1980年开始,双侧宫颈淋巴结解剖技术越来越关注,逐渐报告了有利的长期结果。 1990年社会进行的全国调查问卷调查表明,通过遵循三场淋巴结解剖技术,通过遵循双场淋巴结解剖技术来实现更有利的长期结果。从那时起,已经认识到三场淋巴结解剖技术并广泛用作治疗食管癌的标准外科手术。在临床研究中,检查了各种术前和术后辅助疗法的效用,术前化疗被认为是治疗指南中的标准治疗。此外,已经开发了较少的侵入性外科方法,包括内窥镜和机器人辅助手术,现在应用于一般实践。然而,不可切除和复发性食管癌仍然难以治疗,并且应开发额外的治疗方法。

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