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首页> 外文期刊>Artificial cells, nanomedicine, and biotechnology. >Carbon dots from Artemisiae Argyi Folium Carbonisata: strengthening the anti-frostbite ability
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Carbon dots from Artemisiae Argyi Folium Carbonisata: strengthening the anti-frostbite ability

机译：来自Artemisiae Argyi Folarium Carbanisata的碳点：加强抗冻冻土能力

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In this study, novel carbon dots (CDs) were discovered and separated from Artemisiae Argyi Folium Carbonisata (AAFC) aqueous extract. AAFC-CDs were characterised by a series of methods, mainly including electron microscopy, optical technology and X-ray photoelectron spectroscopy (XPS). Results displayed that AAFC-CDs with a quantum yield (QY) around 0.19% had a size distribution between 6.0 and 10.0?nm and possessed a nearly spherical shape, with a lattice spacing of 0.369?nm. In mice, AAFC-CDs reduced the tissue damage, ear frostbite, and body stiffness caused by cold, and provided energy by increasing the use of blood glucose. The mechanism may be by decreasing concentration of IL-1βk, TNF-α and reducing the rise in blood glucose levels caused by frostbite. This study is the first to indicate that CDs may be the active constituent of AAFC against frostbite, suggesting their potential for clinical applications.
机译：在该研究中，发现并分离了新的碳点（CDS）和分离了Artemisiae Argyi Folarium Carbanisata（AAFC）含水提取物。 AAFC-CD的特征在于一系列方法，主要包括电子显微镜，光学技术和X射线光电子能谱（XPS）。结果显示，具有量子产率（QY）的AAFC-CD约为0.19％的尺寸分布在6.0和10.0≤nm之间，并具有几乎球形的形状，晶格间距为0.369Ω·纳米。在小鼠中，AAFC-CD通过增加血糖的使用减少了由冷引起的组织损伤，耳冻伤和体刚度，并提供了能量。该机制可以通过降低IL-1βK，TNF-α的浓度，并降低冻伤引起的血糖水平的上升。本研究是第一个表明CD可以是AAFC对冻伤的活性成分，表明它们对临床应用的潜力。

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