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Patient perceived barriers to exercise and their clinical associations in difficult asthma

机译:患者感知运动的障碍及其在困难的哮喘中的临床关联

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Background:Exercise is recommended in guidelines for asthma management and has beneficial effects on symptom control, inflammation and lung function in patients with sub-optimally controlled asthma. Despite this, physical activity levels in patients with difficult asthma are often impaired. Understanding the barriers to exercise in people with difficult asthma is crucial for increasing their activity, and in implementing successful, disease modifying, and holistic approaches to improve their health.Methods:62 Patients within the WATCH Difficult Asthma Cohort (Southampton, UK) completed an Exercise Therapy Burden Questionnaire (ETBQ). The results were analyzed with contemporaneous asthma-related data to determine relationships between perceived exercise barriers and asthma and comorbidity characteristics.Results:Patients were reflective of a difficult asthma cohort, 66% were female, and 63% were atopic. They had a high BMI (median [inter-quartile range]) of 29.3 [25.5-36.2], age of 53.5 [38.75, 65.25], impaired spirometry with FEV1 73% predicted [59.5, 86.6%] and FEV/FVC ratio of 72 [56.5, 78.0] and poor symptom control, as defined by an Asthma Control Questionnaire (ACQ6) result of 2.4 [1.28, 3.2]. A high perceived barriers to exercise score was significantly correlated with increased asthma symptoms (r?=?0.452, p??0.0001), anxiety (r?=?0.375, p?=?0.005) and depression (r?=?0.363, p?=?0.008), poor quality of life (r?=?0.345, p?=?0.015) and number of rescue oral steroid courses in the past 12?months (r?=?0.257, p?=?0.048). Lung function, blood eosinophil count, FeNO, Njimegen and SNOT22 scores, BMI and hospitalisations in the previous year were not related to exercise perceptions.Conclusion:In difficult asthma, perceived barriers to exercise are related to symptom burden and psychological morbidity. Therefore, exercise interventions combined with psychological input such as CBT to restructure thought processes around these perceived barriers may be useful in facilitating adoption of exercise.? The Author(s) 2020.
机译:背景:建议在哮喘管理准则中锻炼,对患者患者患者症状控制,炎症和肺功能有益的疗效。尽管如此,患有困难哮喘患者的身体活性水平通常受损。了解患有困难患者的障碍的障碍对于增加他们的活动至关重要,并在实施成功,疾病修改和整体方法来改善其健康。方法:62名患者困难的哮喘队(南安普敦,英国)完成了运动治疗负担调查问卷(ETBQ)。用同期哮喘相关数据分析结果,以确定感知运动障碍和哮喘和合并症的关系。结果:患者反映困难的哮喘队列,66%是雌性,63%是特应性。它们具有29.3 [25.5-36.2]的高BMI(中位数[间隙范围]),年龄为53.5岁[38.75,65.25],损伤肺活量测定法,FEV1 73%预测[59.5,86.6%]和FEV / FVC比率72 [56.5,78.0]和症状控制差,如哮喘控制问卷(ACQ6)所定义的2.4 [1.28,3.2]。对运动得分的高感知障碍与哮喘增加显着相关(R?= 0.452,P?<?0.0001),焦虑(R?= 0.375,P?= 0.005)和抑郁(R?= 0.363 ,p?= 0.008),生活质量差(R?= 0.345,p?=?0.015)和过去12个月的救援口服类固醇课程数月(R?= 0.257,P?= 0.048 )。肺功能,血嗜酸性粒细胞计数,FENO,NJIMEGEN和SNOT22分数,上一年的BMI和住院与运动感知无关。结论:在困难的哮喘中,运动障碍与症状负担和心理发病有关。因此,运动干预与心理投入相结合,例如CBT以重组这些感知障碍的思想过程可能是有助于促进运动的可用。?作者2020年。

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