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首页> 外文期刊>Arquivo Brasileiro de Medicina Veterinaria e Zootecnia >Linfoma extranodal em um cachorro-do-mato-vinagre (Speothos venaticus) - relato de caso
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Linfoma extranodal em um cachorro-do-mato-vinagre (Speothos venaticus) - relato de caso

机译：小猪醋（Speothhos venaticus）的外延淋巴瘤 - 案例报告

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A captive 7-year-old male bush dog (Speothos venaticus) was diagnosed with lymphoma affecting the kidneys, adrenal glands, liver, and spleen. The animal developed renal failure and was euthanized due to poor prognosis. Grossly, both kidneys were enlarged with multiple nodules. Histologically, the neoplasm was an infiltrative and poorly demarcated round cell tumor. Two morphologically distinct cell populations were observed, smaller cells with a lymphocytic morphology, and another population of larger and pleomorphic cells. Most of the smaller cell population, approximately 40% of the population within the neoplasm, were CD3 positive. Neoplastic cells were CD45, CD11d, and granzime B positive, and negative for CD20, CD79a, PAX5, CD163, and myeloperoxidase. This is the first reported case of lymphoma in a bush dog. This report demonstrated the suitability of several cell surface markers for differential diagnosis of round cell tumors in this species.
机译：一个俘虏7岁的男性灌木狗（Speothos venaticus）被诊断出患有影响肾脏，肾上腺腺体，肝脏和脾脏的淋巴瘤。动物发育肾功能衰竭，并且由于预后差而被安乐死。严重的情况下，两种肾脏都被多个结节放大。组织学上，肿瘤是一种渗透和划分的圆形细胞肿瘤。观察到两种形态学上不同的细胞群，细胞具有淋巴细胞形态的细胞，以及另一个较大和茂物细胞的群体。大多数较小的细胞群，大约40％的肿瘤内的群体，是CD3阳性。肿瘤细胞是CD45，CD11d和Granzime B阳性，CD20，CD79a，pAX5，CD163和髓氧化酶的阴性。这是灌木狗的第一个报告的淋巴瘤病例。本报告证明了几种细胞表面标志物在该物种中进行鉴别诊断圆细胞瘤的差异诊断。

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