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首页> 外文期刊>Arquivo Brasileiro de Medicina Veterinaria e Zootecnia >Escherichia coli multirresistente isolada de c?o com histórico de urolitíase: relato de caso
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Escherichia coli multirresistente isolada de c?o com histórico de urolitíase: relato de caso

机译：从尿路术病史中分离的大肠杆菌多刺激：案例报告

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Bacterial resistance is a reality in both human and veterinary health, it limits the therapeutic arsenal and raises the costs of the patient’s treatment. A dog with signs of cystitis received treatment with 5mg/kg enrofloxacin at three consecutive times, with low effectiveness. The presence of urethral uroliths was identified and urohydropulsion was done. The animal presented a new obstruction, for which a cystotomy was performed, but continued with signs of infection. Uroculture and antimicrobial susceptibility test were then performed. Escherichia coli was identified, which was resistant to 13 antibiotics, being sensitive only to piperacillin-tazobactam and amikacin. In the screening test for β-lactamase, the production of ESβL was detected. The qPCR indicated the presence of the bla CTXm, bla DHA, bla OXA, bla IMP, bla TEM, bla GIM, bla SIM, bla SPM and bla SME genes, which may lead to a phenotypic resistance profile for ampicillin, amoxicillin-clavulanate, aztreonam, cefepime cefoxitin, cefuroxime, ceftazidime, ceftriaxone, imipenem, and piperacillin-tazobactam. This case reaffirms the value that laboratory analysis adds to the diagnosis and treatment of cystitis and urolithiasis, which can define the direction of evolution of the prognosis and the speed at which the patient's health will be restored.
机译：细菌抗性是人类和兽医健康的现实，它限制了治疗武器，并提高了患者治疗的成本。一只患有膀胱炎迹象的狗在连续三次中接受5mg / kg富含缬沙星的治疗，效率低。鉴定了尿道尿嘧啶的存在，并进行氟氯丙酮。该动物提出了一种新的梗阻，进行了一种囊状切开术，但继续感染迹象。然后进行尿素培养和抗微生物易感性试验。鉴定了大肠杆菌，其耐药于13个抗生素，仅对Piperacillin-Tazobactam和Amikacin敏感。在β-内酰胺酶的筛选试验中，检测ESβ1的产生。 QPCR表示存在BLA CTXM，BLA DHA，BLA OXA，BLA IMP，BLA TEM，BLA GIM，BLA SIM，BLA SPM和BLA中小企业基因，这可能导致氨苄青霉素，阿莫西林 - 克拉维酸酯的表型电阻曲线， Aztreonam，Cefepime Cefoxitin，Cefuroxime，Ceftazidime，Ceftriaxone，Imipenem和Piperacillin-Tazobactam。这种情况重申实验室分析增加了膀胱炎和尿道病的诊断和治疗的价值，可以定义预后的演变方向和患者健康将恢复的速度。

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