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首页> 外文期刊>Indian Journal of Medical and Paediatric Oncology >The Conundrum of Dual Primary Malignancies: Four Years' Experience of a Single Tertiary Care Institute in India
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The Conundrum of Dual Primary Malignancies: Four Years' Experience of a Single Tertiary Care Institute in India

机译：双重初级恶性肿瘤的难题：印度单一第三节护理学院的四年经验

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Background: Encountering more than one malignancy in a cancer patient is no longer uncommon; this increasing incidence is mostly attributable to the improvements in life expectancy, awareness, and diagnostic facilities. This article aims to highlight this institute's experience in diagnosis and treatment of patients of multiple primary malignancies and a comprehensive review of literature. Materials and Methods: This is a descriptive study of retrospectively collected data of a single institution over 4 years from 2013 to 2016. Known cases of cancer who were diagnosed with a second primary malignancy were included in the study. Various details such as age, sex, site of disease, temporal relation of two cancers (synchronous or metachronous), family history, tobacco use, treatment given, and survival at 1 year were recorded, organized in a tabular form, analyzed, and described. Results: A total of 29 cases of dual malignancies comprising 0.74% of a total of 3879 patients of cancer were encountered. Seventy-two percent of the cases were metachronous and 5 years was the mean time interval between tumors. There was a female preponderance, and the average age was 56 years. Breast was the most common site of malignancy. At 1 year from diagnosis of second primary, 69% of the patients were alive and 27% were disease-free. Conclusion: Second primary in a patient of cancer is becoming increasingly common and the suspicion of the same should always be borne in mind during follow-up. Prognosis as well as intent of treatment depends on respective stages of the two malignancies.
机译：背景：在癌症患者中遇到一个以上的恶性肿瘤不再罕见;这种增加的发病率主要是归因于预期寿命，意识和诊断设施的改善。本文旨在突出本研究所的多发性恶性肿瘤患者诊断和治疗的经验以及对文学的全面审查。材料和方法：这是从2013年至2016年从4年来回顾性收集的回顾性收集的单一机构数据的描述。已知的癌症患者被诊断出患有第二个原发性恶性肿瘤。各种细节，如年龄，性别，疾病，两种癌症的时间关系（同步或同学），家庭历史，烟草使用，治疗给出的，以表格形式组织，分析和描述。结果：遇到了29例双重恶性肿瘤，总共有0.74％的癌症患者的0.74％。百分之七十二个病例的同时和5年是肿瘤之间的平均时间间隔。女性优势，平均年龄为56岁。乳房是恶性肿瘤最常见的遗址。在诊断诊断的1年后，69％的患者还活着，27％是无病的。结论：癌症患者中的第二次初级常见变得越来越普遍，并且在随访期间应该始终承担同样的疑虑。预后以及治疗的目的取决于两种恶性肿瘤的各个阶段。

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