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首页> 外文期刊>Indian Journal of Medical and Paediatric Oncology >Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience
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Analysis of relapsed/refractory Hodgkin lymphoma treated with autologous transplantation: A single-center experience

机译：自体移植治疗复发/难治性霍奇金淋巴瘤分析：单中心经验

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Introduction: Hodgkin lymphoma (HL) is one of the common lymphomas with high cure rate. Aims: The aim was to study the outcome of relapsed/refractory HL treated with autologous transplantation. Objectives: The objective was to study the overall survival, overall response, and disease-free survival of the relapsed/refractory HL after autologous transplantation. Methods: It was a retrospective study conducted over a period of 8 years in our center using computer-based database and medical records as the data source. Results: A total of 22 patients were diagnosed with relapsed/refractory HL of which majority of cases were male patients (59%) with a mean age of 29 years (range: 15–57 years) and were Stage 4A (40.9%), with nodular sclerosis (54.5%). The overall response rate was 81.8% with 9.1% complete response, 72.7% partial response, and 4.5% stable disease; the overall survival was 77.92 ± 6.65 months, and disease-free survival was 69.66 ± 8.13 months. Conclusion: Autologous stem cell transplant plays an integral role in the treatment of patients with relapsed/refractory Hodgkin lymphoma.
机译：简介：霍奇金淋巴瘤（HL）是具有高固化率的常见淋巴瘤之一。目的：目的是研究自体移植治疗的复发/难治性H1的结果。目的：目的是在自体移植后研究复发/难治性HL的整体存活，整体反应和无病存存。方法：是在我们的中心在8年内进行的回顾性研究，使用基于计算机的数据库和医疗记录作为数据源。结果：共有22名患者被诊断出患有复发/难治性HL，其中大多数病例是男性患者（59％），平均年龄为29岁（范围：15-57岁），阶段4A（40.9％），结节性硬化症（54.5％）。整体反应率为81.8％，完全响应9.1％，部分反应72.7％，稳定疾病4.5％;整体存活率为77.92±6.65个月，无病生存率为69.66±8.133个月。结论：自体干细胞移植在患有复发/难治性霍奇金淋巴瘤患者的治疗中起着积分作用。

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