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首页> 外文期刊>Indian Journal of Medical and Paediatric Oncology >Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report
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Primary rectal lymphoma with synchronous liver involvement: An extremely rare case report

机译：具有同步肝脏的初级直肠淋巴瘤参与：一个极其罕见的病例报告

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Both primary rectal lymphoma (PRL) and primary hepatic lymphoma are rare entities, concomitant NHL in rectum and liver is an extremely rare coincidence. Cases of primary colonic lymphoma however can be found in literature. We report an extremely rare case of PRL with synchronous liver involvement after obtaining written informed consent, with a review of available literature. The case was provisionally diagnosed to be an adenocarcinoma of rectum with liver metastasis, with final confirmation on immunohistochemistry. PRL with synchronous liver involvement is an extremely rare coincidence. It is usually confused with more common adenocarcinoma of rectum with liver metastasis posing diagnostic challenges. The optimal management of PRL has never been validated through randomized trials. The treatment options include chemotherapy, radiation, surgical treatment, or a combination of these. Chemotherapeutic agents of choice are the cyclophosphamide, doxorubicin, vincristine, and prednisone regimen, with or without monoclonal antibody rituximab.
机译：初级直肠淋巴瘤（PRL）和原发性肝淋巴瘤都是罕见的实体，直肠和肝脏中的伴随NHL是一个极其罕见的巧合。然而，在文献中可以发现原发性结肠淋巴瘤病例。在获得书面知情同意之后，我们报告了一个极其罕见的PRL案例，同时肝脏参与，并对现有文献进行了审查。该病例被局部被诊断为具有肝转移的直肠腺癌，最终确认免疫组织化学。具有同步肝脏参与的PRL是一种极其罕见的巧合。通常与肝转移造成诊断挑战的肝脏转移更常见的直肠腺癌混淆。 PRL的最佳管理从未通过随机试验进行了验证。治疗选择包括化疗，辐射，手术治疗或这些组合。选择的化学治疗剂是环磷酰胺，多柔比蛋白，长春螯合物和泼尼松方案，有或没有单克隆抗体利妥昔单抗。

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