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首页> 外文期刊>International Journal of Biomedical and Advance Research >Comparative studies on Effect of Jadelle, Depoproveral and implanon Contraceptives on APOA1 and APO B Concentration in Females Attending a Tertiary Hospital in Southern Nigeria
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Comparative studies on Effect of Jadelle, Depoproveral and implanon Contraceptives on APOA1 and APO B Concentration in Females Attending a Tertiary Hospital in Southern Nigeria

机译：Jadelle，剥离和Implanon避孕药对尼日利亚大专院校高等院医院ApoA1和Apo B浓度的对比研究

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Background: Apolipoproteins function as structural components of lipoprotein particles, cofactors for enzymes and ligands for cell-surface receptors. Apo A1 a major component of high density lipoprotein, while Apo B which is a primary apolipoprotein of chylomicrons, VLDL, IDL, and LDL when in reference to both heart and vascular diseases indictment, helps in the transportation of fat molecules (lipids): cholesterol inclusive around the body. The study was carried out to compare Apo A1 and Apo levels in women on Implanon, Jadelle and Depo-Provera- the three most popular steroidal contraceptives used in south-south part of Nigeria.Methodology: Ninety (90) female subjects in three groups of 30 each were recruited for Implanon, Jadelle and Depo-provera. Apo A1 and Apo B were determined using turbidimetric method on Baseline, 3rd, 6th, 9th and 12th month blood samples collected from these subjects.Result: The result of the study showed that there was increased significant difference in Apo A concentration of females on Implanon, Jadelle and Depo-provera at 3rd, 6th, 9th and 12th months compared with the baseline. Also, a significant increased difference (P0.05) was observed at the 3rd, 6th, 9th and 12th month in ApoB when compared with the baseline. A monthly dependent increase was observed in the three contraceptives studied for ApoB, a pattern which is also observed in ApoA1 in jadelle and depo-provera only.Conclusion: The study showed that there were significant increased changes in Apo A1 and ApoB concentrations in female subjects taking Implanon, Jadelle and Depo-provera at different months.
机译：背景：脂蛋白用作脂蛋白颗粒的结构组分，用于细胞表面受体的酶和配体的辅助粘液剂。 Apo A1高密度脂蛋白的主要成分，而Apo B是Chylomrons，VLDL，IDL和LDL的主要载脂蛋白，当参考心脏和血管疾病起诉时，有助于脂肪分子的运输（脂质）：胆固醇在身体周围包容。该研究进行了比较inallanon，Jadelle和Depo-Provera的妇女APO A1和APO水平 - 在尼日利亚南部的三种最受欢迎​​的甾体避孕药中。方法：九十（90）个女性受试者30人被招募了inclanon，Jadelle和Depo-Provera。从这些主题收集的基线，第3，第6号，第9个月和第12个月血液样本上使用浊度法测定APO A1和APO B.结果：该研究的结果表明，APO对Implanon的浓度增加了显着差异，与基线相比，Jadelle和Depo-Provera在3号，第6号，第9和第12个月。此外，与基线相比，在Apob中的第3,6，第6号，第9个月和第12个月内观察到显着增加的差异（P <0.05）。在研究的三种避孕措施中观察到每月依赖于Apob的避孕药，该模式在Jadelle和Depo-Provera的Apoa1中也观察到。结论：该研究表明，女性受试者的APO A1和ApoB浓度有显着增加。在不同的月份服用Implanon，Jadelle和Depo-Provera。

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