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首页> 外文期刊>International journal of endocrinology >Serum 25(OH)D Level and Parathyroid Hormone in Chinese Adult Population: A Cross-Sectional Study in Guiyang Urban Community from Southeast of China
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Serum 25(OH)D Level and Parathyroid Hormone in Chinese Adult Population: A Cross-Sectional Study in Guiyang Urban Community from Southeast of China

机译:中国成人人口中的血清25(OH)D水平和甲状旁腺激素:来自中国东南部的贵阳城市社区的横断面研究

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摘要

Objective. To evaluate vitamin D status and serum parathyroid hormone (IPTH) of healthy adults living in Guiyang.Design and Participants. We conducted a cross-sectional evaluation in the General Community in Guiyang by cluster sampling method. The data was a part of 1510 participants (634 men, 876 women) aged 20–79 years median 45.2 years from November 2009 to February 2010 in Guiyang Health Measures Survey.Measurements. Aradioimmunoassay was used to measure the level of 25-hydroxyvitamin D [25(OH)D] and intact parathyroid hormone (iPTH).Results.The mean serum 25(OH)D level was (20.4 ± 9.0) ng/mL and the highest level among participants aged 40–59 years (22.8 ng/mL). The mean serum PTH level was (32.1 ± 13.7) pg/mL and the lowest level among participants aged 40–50 years (30.8 ng/mL). Serum 25(OH)D was below 50 nmol/liter in 52.3%, below 75 nmol/liter in 84.6%, and above 75 nmol/liter in 15.4% of the respondents. Secondary hyperparathyroidism was 5.4% (5.4% among men and 4.6% among women). The prevalence of secondary hyperparathyroidism increased (5.8%, 6.5%, and 7.1%, resp.) with decreasing serum 25(OH)D levels among subjects who were 30 to 20, 19.9 to 10, and <10 ng/mL, respectively. Serum 25(OH)D was inversely associated with serum PTH.Conclusions. Vitamin D insufficiency and its complication of secondary hyperparathyroidism are common.
机译:客观的。评估生活在贵阳和参与者的健康成年人的维生素D状态和血清甲状旁腺激素(IPTH)。我们通过集群采样方法对贵阳的普通社区进行了横截面评价。该数据是1510名参与者(634名男性,876名女性)的一部分,年龄在2009年11月至2010年11月至2010年2月在贵阳健康措施调查中的25.2岁。 AradioImmunoassay用于测量25-羟基vitamin d [25(OH)D]和完整的甲状旁腺激素(IPTH)。结果。意味着平均血清25(OH)D水平是(20.4±9.0)Ng / ml,最高40-59岁的参与者(22.8 ng / ml)之间的水平。平均血清PTH水平为(32.1±13.7)pg / ml,参与者年龄40-50岁的参与者(30.8ng / ml)。血清25(OH)D低于50米醇/升52.3%,低于75氯/升84.6%,高于75米酚/升15.4%的受访者。继发性甲状旁腺功能亢进症是5.4%(男性中5.4%,女性中4.6%)。继发性甲状旁腺功能亢进的患病率增加(5.8%,6.5%和7.1%,Arch。),其受试者分别降低血清25(OH)D水平,分别为30至20,19.9至10和<10ng / ml。血清25(OH)D与血清Pth.Conclusions逆转。维生素D功能不全及其继发性甲状旁腺功能亢进的并发症是常见的。

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