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首页> 外文期刊>International Journal of Chronic Diseases >Haematological Features and Urologic Pathologies of Diabetic Subjects at Bafoussam Regional Hospital: A Cross-Sectional Study
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Haematological Features and Urologic Pathologies of Diabetic Subjects at Bafoussam Regional Hospital: A Cross-Sectional Study

机译：Bafoussam地区医院糖尿病患者的血液学特征和泌尿病病理：横截面研究

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Background. Diabetes mellitus is at the origin of long-term complications. Objective. This study is aimed at assessing the haematological features and urologic pathologies of diabetic individuals at Bafoussam Regional Hospital. Methods. This was a cross-sectional study conducted from August 2018 to May 2019 in Bafoussam Regional Hospital, West Cameroon. A structured questionnaire was used to gather sociodemographic data. A trained nurse measured the physical and clinical features. Fasting plasma glucose was determined using the glucose meter Accu-Chek Active system. The full blood count (FBC) was carried out using Automatic full Blood Counter, and the CD4, CD3, and CD8 T-cell counts were determined using the flow cytometry method. Results. There were 455 diabetic patients, and 50 nondiabetic patients were included. The mean age of diabetic patients (56.94±14.33 years) was higher compared to that of nondiabetic individuals (34.76±14.35 years) (p0.001). There was a significant relationship between married individuals (χ2=79.19, p0.001, and df=4), housewife and retired (χ2=1117.38, p0.001, and df=37), old age (40 years and above) (χ2=79.11, p0.001, and df=3), and diabetes status. Diabetic patients had an odds of 5.52 to experience a urinary urge as compared to the controls (p0.001, 95% CI=2.15-14.22). The majority of haematological parameters were negatively but not significantly correlated with diabetes. Binary logistic regression shows that MCV (r=?0.251, OR=0.778, and 95% CI=0.617–0.983; p=0.035) and RDW-CV (r=?0.477, OR=0.620, and 95% CI=0.454–0.848; p=0.003) negatively influence the probability of having diabetes. RDW-SD (r=0.135, OR=1.144, and 95% CI=1.014–1.291; p=0.029) positively influences the probability of having diabetes. Conclusion. This study revealed a significant haematological and urological profile difference according to diabetes status. Research and interventions targeted at diabetic population could help close gaps in diabetes complications.
机译：背景。糖尿病患者处于长期并发症的起源。客观的。本研究旨在评估Bafoussam地区医院的糖尿病患者的血液学特征和泌尿科病理。方法。这是从2018年8月到2019年5月在西喀麦隆的Bafoussam地区医院进行的横断面研究。使用结构化问卷来收集社会渗透数据。训练有素的护士测量了物理和临床特征。使用葡萄糖仪Accu-Chek活性系统测定空腹血浆葡萄糖。使用自动全血计进行全血计数（FBC），使用流式细胞术法测定CD4，CD3和CD8 T细胞计数。结果。有455名糖尿病患者，包括50名非糖尿病患者。与非糖尿病个体相比，糖尿病患者的平均年龄（56.94±14.33岁）（34.76±14.35岁）（P <0.001）。已婚人士（χ2= 79.19，P <0.001和DF = 4）之间存在重要的关系，家庭主妇和退休（χ2= 1117.38，p <0.001和df = 37），老年（40岁及以上）（ χ2= 79.11，p <0.001和df = 3）和糖尿病状态。与对照相比，糖尿病患者的可能性为5.52的尿急尿动（P <0.001,95％CI = 2.15-14.22）。大多数血液学参数是负面的，但与糖尿病没有显着相关。二进制逻辑回归显示MCV（r = 0.251，或= 0.778，95％CI = 0.617-0.983; p = 0.035）和RDW-CV（r = 0.477，或= 0.620，以及95％CI = 0.454- 0.848; p = 0.003）对具有糖尿病的概率产生负面影响。 RDW-SD（r = 0.135，或= 1.144，95％CI = 1.014-1.291; p = 0.029）积极影响患有糖尿病的可能性。结论。本研究揭示了根据糖尿病状态的显着血液神经性和泌尿外景差异。针对糖尿病群的研究和干预措施可以帮助患糖尿病并发症的差距。

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